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DOCK2

dedicator of cytokinesis 2

Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. Activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. May also participate in IL2 transcriptional activation via the activation of RAC2.

Gene Name: dedicator of cytokinesis 2
Synonyms: DOCK2, Dedicator of cyto-kinesis 2, Dedicator of cytokinesis 2, KIAA0209
Target Sequences: D86964 Q92608 Q92608

☰ Filters
Products
Antibodies (33)
Primary (33)
DOCK2 (33)
Human (33)
Mouse (11)
Rat (1)
Chimpanzee (3)
Horse (6)
IHC (7)
IHC-P (2)
WB (28)
ELISA (2)
IF (3)
IP (2)
Peptide-ELISA (1)
rabbit (25)
mouse (7)
goat (1)
IgG (18)
IgG2a (6)
IgG2a,k (1)
monoclonal mc (7)
polyclonal pc (26)
2F4 (1)
OTI4E12 (2)
OTI7G2 (2)
UMAB142 (2)
APC (1)
APC Conjugated (2)
Biotin Conjugated (3)
Carrier-free (3)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (2)
Unconjugated (18)
aa390-635 (8)
aa1544-1830 (6)
C-Terminus (4)
Internal (2)
aa1775-1825 (1)
aa420-642 (1)
aa550-600 (1)
No (33)
DOCK2 Antibody - Immunohistochemical staining of paraffin-embedded human lung cancer using anti-DOCK2 clone UMAB142 mouse monoclonal antibody at 1:200 dilution of 1.0 mg/mL using Polink2 Broad HRP DAB for detection.requires HIER with with citrate pH6.0 at 110C for 3 min using pressure chamber/cooker. IHC staining shows tumor cells are negative however infiltrating lymphocytes strongly positive.
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DOCK2 Mouse anti-Human Monoclonal (aa1544-1830) (UMAB142) Antibody
Human
IF, IHC, WB
Unconjugated
100 µl/$493
DOCK2 Antibody - Immunohistochemical staining of paraffin-embedded human lung cancer using anti-DOCK2 clone UMAB142 mouse monoclonal antibody at 1:200 dilution of 1.0 mg/mL using Polink2 Broad HRP DAB for detection.requires HIER with with citrate pH6.0 at 110C for 3 min using pressure chamber/cooker. IHC staining shows tumor cells are negative however infiltrating lymphocytes strongly positive.
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DOCK2 Mouse anti-Human Monoclonal (aa1544-1830) (Carrier-free) (UMAB142) Antibody
Human
IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$539
DOCK2 Antibody - IHC of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-DOCK2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).
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DOCK2 Mouse anti-Human Monoclonal (aa1544-1830) (OTI7G2) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
DOCK2 Antibody - IHC of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-DOCK2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).
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DOCK2 Mouse anti-Human Monoclonal (aa1544-1830) (Carrier-free) (OTI7G2) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
DOCK2 Antibody - IHC of paraffin-embedded Carcinoma of Human lung tissue using anti-DOCK2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
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DOCK2 Mouse anti-Human Monoclonal (aa1544-1830) (OTI4E12) Antibody
Human
IHC, IHC-P
Unconjugated
100 µl/$434
DOCK2 Antibody - IHC of paraffin-embedded Carcinoma of Human lung tissue using anti-DOCK2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
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DOCK2 Mouse anti-Human Monoclonal (aa1544-1830) (Carrier-free) (OTI4E12) Antibody
Human
IHC
Unconjugated, Carrier-free
100 µg/$511
DOCK2 Antibody - Staining HepG2 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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DOCK2 Rabbit anti-Human Polyclonal Antibody
Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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DOCK2 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
DOCK2 Antibody - Detection of human DOCK2 by western blot. Samples: Whole cell lysate (50 µg) from HeLa, HEK293T, and Jurkat cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-DOCK2 antibody used for WB at 0.1 µg/ml. Detection: Chemiluminescence with an exposure time of 10 seconds.
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DOCK2 Rabbit anti-Human Polyclonal (aa1775-1825) Antibody
Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
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DOCK2 Rabbit anti-Mouse Polyclonal (Internal) Antibody
Mouse, Horse, Human
WB
Unconjugated
100 µg/$854
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DOCK2 Rabbit anti-Mouse Polyclonal (HRP) Antibody
Mouse, Horse, Human
WB
HRP Conjugated
100 µl/$1,073
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DOCK2 Rabbit anti-Mouse Polyclonal (Biotin) Antibody
Mouse, Horse, Human
WB
Biotin Conjugated
100 µl/$1,073
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DOCK2 Rabbit anti-Mouse Polyclonal (FITC) Antibody
Mouse, Horse, Human
WB
FITC Conjugated
100 µl/$1,073
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DOCK2 Rabbit anti-Mouse Polyclonal (APC) Antibody
Mouse, Horse, Human
WB
APC Conjugated
100 µl/$1,073
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DOCK2 Rabbit anti-Mouse Polyclonal (PE) Antibody
Mouse, Horse, Human
WB
PE Conjugated
100 µl/$1,073
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DOCK2 Mouse anti-Human Monoclonal (2F4) Antibody
Human
ELISA
Unconjugated
100 µg/$423
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DOCK2 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µl/$749
DOCK2 Antibody - Western blot analysis of extracts of Jurkat cells.
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DOCK2 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
20 µl/$275; 100 µl/$389; 200 µl/$503
DOCK2 Antibody - Western blot analysis of extracts of Jurkat cells using DOCK2 Polyclonal Antibody.
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DOCK2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
120 µl/$403; 200 µl/$529
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DOCK2 Goat anti-Human Polyclonal (aa420-642) Antibody
Human
WB
Unconjugated
100 µg/$919
DOCK2 Antibody - Western blot of DOCK2 antibody.
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DOCK2 Rabbit anti-Human Polyclonal (aa390-635) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
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DOCK2 Rabbit anti-Human Polyclonal (aa550-600) Antibody
Human
IP
Unconjugated
10 µg/$295; 100 µl/$514
DOCK2 Antibody - DOCK2 antibody Western blot of THP-1 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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DOCK2 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Mouse, Human, Chimpanzee
WB
HRP Conjugated
100 µl/$469
DOCK2 Antibody - DOCK2 antibody Western blot of THP-1 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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DOCK2 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Mouse, Human, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
DOCK2 Antibody - DOCK2 antibody Western blot of THP-1 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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DOCK2 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Mouse, Human, Chimpanzee
WB
FITC Conjugated
100 µl/$469
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).