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DNTT / TdT

DNA nucleotidylexotransferase

DNTT / TdT is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.

Gene Name: DNA nucleotidylexotransferase
Synonyms: DNTT, DNA nucleotidylexotransferase, TDT, Terminal addition enzyme, Terminal transferase
Target Sequences: NM_004088 NP_004079.3 P04053

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Products
Proteins (6)
Over-Expression Lysate (2)
Recombinant (4)
DNTT / TdT (6)
No (6)
6His, N-terminus (1)
GST, N-terminus (1)
GST, N-terminus + His, C-terminus (1)
His, N-Terminal (1)
Myc-DDK (Flag) (2)
Human (5)
293T Cells (1)
E. coli (3)
HEK 293 Cells (1)
Wheat Germ Extract (1)
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E. coli
6His, N-terminus
62.6 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
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HEK 293 Cells
Myc-DDK (Flag)
58.4 kDa
100 µg/$494
DNTT / TdT Protein
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E. coli
GST, N-terminus + His, C-terminus
84.2 kDa
50 µg/$419
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293T Cells
Myc-DDK (Flag)
58.4 kDa
20 µg/$150
DNTT / TdT Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
DNTT / TdT Protein
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E. coli
His, N-Terminal
58 kDa
10 µg/$265; 100 µg/$365; 50 µg/$315
Viewing 1-6 of 6 product results


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Products: Proteins


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).