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DNT / NT5C

5', 3'-nucleotidase, cytosolic

DNT / NT5C is a nucleotidase that catalyzes the dephosphorylation of the 5' deoxyribonucleotides (dNTP) and 2'(3')-dNTP and ribonucleotides, but not 5' ribonucleotides. Of the different forms of nucleotidases characterized, this enzyme is unique in its preference for 5'-dNTP. It may be one of the enzymes involved in regulating the size of dNTP pools in cells. Alternatively spliced transcript variants have been found for this gene.

Gene Name: 5', 3'-nucleotidase, cytosolic
Synonyms: NT5C, 5', 3'-nucleotidase, cytosolic, 5, 3-nucleotidase, cytosolic, CdN, Deoxy-5-nucleotidase 1, DNT1, DNT, p5N2, PN-I, UMPH2, DNT-1, PN-II
Target Sequences: NM_014595 NP_055410.1 Q8TCD5

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Products
Proteins (6)
Over-Expression Lysate (2)
Recombinant (4)
DNT / NT5C (6)
No (6)
GST (1)
His, N-Terminal (1)
Myc-DDK (Flag) (3)
Human (4)
Mouse (1)
293T Cells (1)
E. coli (2)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
DNT / NT5C Protein - 12.5% SDS-PAGE of human NT5C stained with Coomassie Blue
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Wheat Germ Extract
GST
39.7 kDa
10 µg/$479; 25 µg/$670
DNT / NT5C Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
23.2 kDa
100 µg/$494
DNT / NT5C Protein - Purified recombinant protein NT5C was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
23.2 kDa
20 µg/$1,107
DNT / NT5C Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
23.2 kDa
20 µg/$150
DNT / NT5C Protein - Recombinant 5',3'-Nucleotidase, Cytosolic (NT5C) by SDS-PAGE
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E. coli
His, N-Terminal
25.5kDa
10 µg/$274; 50 µg/$400; 200 µg/$797; 100 µg/$637; 1 mg/$1,870; 500 µg/$1,424; 5 mg/$2,832; 2 mg/$2,053
DNT / NT5C Protein - Recombinant 5',3'-Nucleotidase, Cytosolic (NT5C) by SDS-PAGE
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E. coli
None
20.3kDa
10 µg/$272; 50 µg/$382; 200 µg/$765; 100 µg/$612; 1 mg/$1,822; 500 µg/$1,383; 5 mg/$2,781; 2 mg/$2,004
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).