DNMT3L

DNA (cytosine-5-)-methyltransferase 3-like

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein with similarity to DNA methyltransferases, but is not thought to function as a DNA methyltransferase as it does not contain the amino acid residues necessary for methyltransferase activity. However, it does stimulate de novo methylation by DNA cytosine methyltransferase 3 alpha and is thought to be required for the establishment of maternal genomic imprints. This protein also mediates transcriptional repression through interaction with histone deacetylase 1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Products

Proteins (11)

Type

Over-Expression Lysate (4)

Recombinant (7)

Target

DNMT3L (11)

Publications

No (11)

Tag

DDK,C-terminus (1)

GST (1)

GST, N-terminus (1)

GST, N-terminus + His, C-terminus (1)

His (2)

Myc-DDK (Flag) (5)

Species

Human (9)

Source

293T Cells (2)

E. coli (3)

HEK 293 Cells (3)

Sf9 Cells (1)

Wheat Germ Extract (2)

Purification

Purified (3)

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Human DNMT3L Protein (Recombinant GST, N-terminus) (aa288-387) - LS-G62329

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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DNMT3L Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G104929

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

43.4 kDa

Price:

100 µg/$494

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Human DNMT3L Protein (Recombinant GST, N-terminus + His, C-terminus) - LS-G145203

Source:

E. coli

Tag:

GST, N-terminus + His, C-terminus

Molecular Weight:

71.5 kDa

Price:

50 µg/$419

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Human DNMT3L Protein (Recombinant DDK,C-terminus) - LS-G142462

Source:

Sf9 Cells

Tag:

DDK,C-terminus

Molecular Weight:

43.5 kDa

Price:

20 µg/$677

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Human DNMT3L Protein (Recombinant His) - LS-G2910

Source:

E. coli

Tag:

His

Price:

50 µg/$411; 250 µg/$985; 10 µg/$276

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Human DNMT3L Protein (Recombinant His) - LS-G2850

Source:

E. coli

Tag:

His

Price:

20 µg/$361; 100 µg/$739; 4 µg/$261

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Human DNMT3L Protein (Recombinant GST) (Full Length) - LS-G33476

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

69.9 kDa

Price:

10 µg/$479; 25 µg/$670

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Human DNMT3L Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G69892

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

43.4 kDa

Price:

20 µg/$1,107

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Human DNMT3L Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G85784

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

43.5 kDa

Price:

20 µg/$150

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Human DNMT3L Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G85785

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

43.4 kDa

Price:

20 µg/$150

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DNMT3L Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G101134

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

43.5 kDa

Price:

100 µg/$494

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