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DNMT3L

DNA (cytosine-5-)-methyltransferase 3-like

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein with similarity to DNA methyltransferases, but is not thought to function as a DNA methyltransferase as it does not contain the amino acid residues necessary for methyltransferase activity. However, it does stimulate de novo methylation by DNA cytosine methyltransferase 3 alpha and is thought to be required for the establishment of maternal genomic imprints. This protein also mediates transcriptional repression through interaction with histone deacetylase 1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Name: DNA (cytosine-5-)-methyltransferase 3-like
Family/Subfamily: C5-methyltransferase
Synonyms: DNMT3L
Target Sequences: NM_013369 NP_037501.2 Q9UJW3

☰ Filters
Antibodies (47)
Proteins (11)
ELISA Kits (2)
Over-Expression Lysate (4)
Primary (47)
Recombinant (7)
Sandwich (2)
DNMT3L (60)
Human (46)
Mouse (21)
Rat (2)
Primate (2)
IHC (14)
IHC-P (3)
WB (42)
ChIP-Seq (1)
ChrIP (3)
ELISA (25)
ICC (2)
IF (7)
IP (6)
Peptide-ELISA (2)
rabbit (45)
mouse (2)
IgG (37)
IgG1 (1)
monoclonal mc (1)
polyclonal pc (46)
S117-9 (1)
96-Well Microplate (1)
96-Well Strip Plate (1)
APC Conjugated (4)
Azide-free (3)
Biotin Conjugated (5)
FITC Conjugated (5)
HRP Conjugated (5)
PE Conjugated (4)
Unconjugated (24)
aa355-381 (7)
aa357-388 (7)
aa389-421 (7)
aa1-387 (1)
aa130-180 (1)
aa152-164 (1)
aa25-75 (1)
aa258-290 (1)
No (60)
Cell Lysates (1)
Plasma (1)
Serum (1)
Tissue Homogenates (1)
DDK,C-terminus (1)
GST (1)
GST, N-terminus (1)
GST, N-terminus + His, C-terminus (1)
His (2)
Myc-DDK (Flag) (5)
Human (9)
293T Cells (2)
E. coli (3)
HEK 293 Cells (3)
Sf9 Cells (1)
Wheat Germ Extract (2)
Purified (3)
DNMT3L Antibody - Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
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DNMT3L Rabbit anti-Human Polyclonal (aa357-388) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
DNMT3L Antibody - Use at 1-10ug/ml. A band of ~45kDa is detected.
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DNMT3L Mouse anti-Human Monoclonal (aa1-387) (S117-9) Antibody
Human
ICC, IF, IHC, WB
Unconjugated
100 µg/$488
DNMT3L Antibody - Immunofluorescence analysis of A549 cells.
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DNMT3L Rabbit anti-Human Polyclonal Antibody
Human
ChIP-Seq, IF, IHC, IP, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
DNMT3L Antibody - 1:100 staining mouse testis tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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DNMT3L Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ChrIP, IF, IHC, IP, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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DNMT3L Mouse anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µg/$705
DNMT3L Antibody - Immunofluorescent analysis of Dnmt3L staining in A549 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 deg C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark.
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DNMT3L Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ChrIP, ICC, IF, IP, WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
DNMT3L ELISA Kit
Select
Sandwich
96-Well Microplate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$902
DNMT3L Antibody - Immunohistochemistry of Rabbit Anti-Human DNMT3L Antibody at 1:500.
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DNMT3L Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
100 µg/$567
DNMT3L Antibody - Immunohistochemistry of paraffin-embedded Rat testis using DNMT3L Polyclonal Antibody at dilution of 1:100 (40x lens).
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DNMT3L Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
Select
DNMT3L Rabbit anti-Human Polyclonal (aa357-388) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
Select
DNMT3L Rabbit anti-Human Polyclonal (aa357-388) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
Select
DNMT3L Rabbit anti-Human Polyclonal (aa357-388) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
Select
DNMT3L Rabbit anti-Human Polyclonal (aa357-388) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
Select
DNMT3L Rabbit anti-Human Polyclonal (aa357-388) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
DNMT3L Rabbit anti-Human Polyclonal (aa357-388) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
Select
DNMT3L Rabbit anti-Human Polyclonal Antibody
Human
ChrIP, IF, WB
Unconjugated
50 µl/$356; 100 µl/$461
DNMT3L Antibody - Immunohistochemistry-Paraffin: Dnmt3L Antibody - Analysis of Dnmt3L in human kidney using Dnmt3L antibody at 5 ug/ml.
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DNMT3L Rabbit anti-Human Polyclonal (aa25-75) Antibody
Human, Primate
IHC, IHC-P, WB
Unconjugated
0.1 mg/$386
DNMT3L Antibody - Immunohistochemistry-Paraffin: Dnmt3L Antibody - Analysis of Dnmt3L in human kidney using Dnmt3L antibody at 5 ug/ml.
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DNMT3L Rabbit anti-Human Polyclonal (aa130-180) Antibody
Human, Primate
IHC, IHC-P, WB
Unconjugated
0.1 mg/$386
Select
DNMT3L Rabbit anti-Human Polyclonal (aa152-164) Antibody
Human
ELISA, IP, WB
Unconjugated
100 µg/$973
Select
DNMT3L Rabbit anti-Mouse Polyclonal (aa389-421) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$734
Select
DNMT3L Rabbit anti-Mouse Polyclonal (aa389-421) (APC) Antibody
Mouse, Human
ELISA, WB
APC Conjugated
200 µl/$952
DNMT3L Antibody - Immunofluorescent analysis of Hela cells using DNMT3L Antibody at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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DNMT3L Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF
Unconjugated
50 µg/$294; 100 µg/$360
Select
DNMT3L Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$351
Select
DNMT3L Rabbit anti-Human Polyclonal (aa355-381) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
DNMT3L Antibody - Western blot of lysate from mouse heart tissue lysate, using Dnmt3l antibody diluted at 1:1000. A goat anti-rabbit IgG H&L (HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20 ug.
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DNMT3L Rabbit anti-Mouse Polyclonal (aa258-290) Antibody
Mouse
Peptide-ELISA, WB
Unconjugated
400 µl/$393
Viewing 1-25 of 60 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).