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2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
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20700 44th Avenue W
Lynnwood, WA 98036
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DNAM-1 / CD226
CD226 molecule
DNAM-1 / CD226 is a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants.
| Gene Name: | CD226 molecule |
| Synonyms: | CD226, Adhesion glycoprotein, CD226 molecule, CD226 antigen, DNAM-1, DNAM1, DNAX accessory molecule-1, TLiSA1, PTA1, DNAX accessory molecule 1 |
| Target Sequences: | NM_006566 NP_006557.2 Q15762 |
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