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DNAL1 encodes an axonemal dynein light chain which functions as a component of the outer dynein arms complex. This complex acts as the molecular motor that provides the force to move cilia in an ATP-dependent manner. The encoded protein is expressed in tissues with motile cilia or flagella and may be involved in the movement of sperm flagella. Alternate splicing results in multiple transcript variants.
Gene Name: | dynein, axonemal, light chain 1 |
Synonyms: | DNAL1, C14orf168, CILD16, Dynein light chain 1, axonemal |
Target Sequences: | NM_031427 NP_113615.2 Q4LDG9 |
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