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DNAJC5 / CSP

DnaJ (Hsp40) homolog, subfamily C, member 5

DNAJC5 / CSP is a member of the J protein family. J proteins function in many cellular processes by regulating the ATPase activity of 70 kDa heat shock proteins. The encoded protein plays a role in membrane trafficking and protein folding, and has been shown to have anti-neurodegenerative properties. The encoded protein is known to play a role in cystic fibrosis and Huntington's disease. A pseudogene of this gene is located on the short arm of chromosome 8.

Gene Name: DnaJ (Hsp40) homolog, subfamily C, member 5
Synonyms: DNAJC5, CLN4, CLN4B, CSP, Cysteine string protein alpha, DNAJC5A, Cysteine string protein
Target Sequences: NM_025219 NP_079495.1 Q9H3Z4

Publications (1)

1
Secretion of misfolded cytosolic proteins from mammalian cells is independent of chaperone-mediated autophagy. Juhyung Lee, Yue Xu, Ting Zhang, Lei Cui, Layla Saidi, Yihong Ye. The Journal of biological chemistry. 2018 September;293:14359-14370. [Full Text Article] [PubMed:30072379] [PMC:PMC6139554]

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Proteins (4)
Over-Expression Lysate (2)
Recombinant (2)
DNAJC5 / CSP (4)
No (4)
GST (1)
Myc-DDK (Flag) (3)
Human (3)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
DNAJC5 / CSP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
22 kDa
20 µg/$150
DNAJC5 / CSP Protein - Purified recombinant protein DNAJC5 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
22 kDa
20 µg/$1,107
DNAJC5 / CSP Protein - 12.5% SDS-PAGE of human DNAJC5 stained with Coomassie Blue
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Wheat Germ Extract
GST
48.5 kDa
10 µg/$479; 25 µg/$670
DNAJC5 / CSP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
22 kDa
100 µg/$494
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).