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Type-VI intermediate filament (IF) which plays an important cytoskeletal role within the muscle cell cytoskeleton. It forms heteropolymeric IFs with desmin and/or vimentin, and via its interaction with cytoskeletal proteins alpha-dystrobrevin, dystrophin, talin-1, utrophin and vinculin, is able to link these heteropolymeric IFs to adherens-type junctions, such as to the costameres, neuromuscular junctions, and myotendinous junctions within striated muscle cells.
Gene Name: | synemin, intermediate filament protein |
Synonyms: | SYNM, Desmuslin, KIAA0353, SYN, Synemin beta, Synemin, DMN, Synemin alpha |
Target Sequences: | AB002351 BAA20810.2 O15061 |
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