DLX5

distal-less homeobox 5

Transcriptional factor involved in bone development. Acts as an immediate early BMP-responsive transcriptional activator essential for osteoblast differentiation. Stimulates ALPL promoter activity in a RUNX2-independent manner during osteoblast differentiation. Stimulates SP7 promoter activity during osteoblast differentiation. Promotes cell proliferation by up-regulating MYC promoter activity. Involved as a positive regulator of both chondrogenesis and chondrocyte hypertrophy in the endochondral skeleton. Binds to the homeodomain-response element of the ALPL and SP7 promoter. Binds to the MYC promoter. Requires the 5'-TAATTA-3' consensus sequence for DNA-binding.

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Products

ELISA Kits (2)

Type

Cell-Based (1)

DNA Binding (1)

Target

DLX5 (2)

Reactivity

Human (2)

Mouse (2)

Rat (2)

Format

12 x 8-Well Microstrips (1)

96-Well Microplate (1)

Publications

No (2)

Sample Type

Adherent Cell Cultures (1)

Cell Lysates (1)

Nuclear Lysates (1)

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Mouse/Human/Rat DLX5 (Cell-Based ELISA) ELISA Kit - LS-F3136

Type:

Cell-Based

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$618

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Mouse/Human/Rat DLX5 (DNA-Binding ELISA) ELISA Kit - LS-F745

Type:

DNA Binding

Format:

12 x 8-Well Microstrips

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Nuclear Lysates

Price:

1 Plate/$694

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