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DLG5

discs, large homolog 5 (Drosophila)

DLG5 is a member of the family of discs large (DLG) homologs, a subset of the membrane-associated guanylate kinase (MAGUK) superfamily. The MAGUK proteins are composed of a catalytically inactive guanylate kinase domain, in addition to PDZ and SH3 domains, and are thought to function as scaffolding molecules at sites of cell-cell contact. The protein encoded by this gene localizes to the plasma membrane and cytoplasm, and interacts with components of adherens junctions and the cytoskeleton. It is proposed to function in the transmission of extracellular signals to the cytoskeleton and in the maintenance of epithelial cell structure. Alternative splice variants have been described but their biological nature has not been determined.

Gene Name: discs, large homolog 5 (Drosophila)
Synonyms: DLG5, Discs large protein LP-DLG, Discs large protein P-dlg, P-dlg, P-DLG5, PDLG, KIAA0583, Large type of P-DLG, LP-DLG, Disks large homolog 5, Placenta and prostate DLG
Target Sequences: NM_004747 NP_004738.3 Q8TDM6

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Proteins (5)
Over-Expression Lysate (2)
Recombinant (3)
DLG5 (5)
No (5)
GST, N-terminus (1)
His-T7, N-terminus (2)
Myc-DDK (Flag) (2)
Human (3)
Mouse (1)
293T Cells (1)
E. coli (2)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (2)
DLG5 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
DLG5 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
213.7 kDa
20 µg/$215
DLG5 Protein - Recombinant Discs, Large Homolog 5 (DLG5) by SDS-PAGE
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E. coli
His-T7, N-terminus
24.8kDa
10 µg/$268; 50 µg/$362; 200 µg/$722; 100 µg/$577; 1 mg/$1,755; 500 µg/$1,325; 5 mg/$2,708; 2 mg/$1,934
DLG5 Protein - Recombinant Discs, Large Homolog 5 (DLG5) by SDS-PAGE
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E. coli
His-T7, N-terminus
24.8kDa
10 µg/$273; 50 µg/$392; 200 µg/$782; 100 µg/$625; 1 mg/$1,847; 500 µg/$1,404; 5 mg/$2,807; 2 mg/$2,029
DLG5 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
213.7 kDa
100 µg/$710
Viewing 1-5 of 5 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).