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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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DLG4 / PSD95

discs, large homolog 4 (Drosophila)

Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B.

Gene Name: discs, large homolog 4 (Drosophila)
Family/Subfamily: MAGUK
Synonyms: DLG4, Disks large homolog 4, Presynaptic density protein 95, PSD95, SAP-90, Synapse-associated protein 90, PSD-95, SAP90, Tax interaction protein 15, Discs large homolog 4
Target Sequences: NM_001365 NP_001356.1 P78352

Publications (2)

1
PSD95 nanoclusters are postsynaptic building blocks in hippocampus circuits. Broadhead MJ, Horrocks MH, Zhu F, Muresan L, Benavides-Piccione R, DeFelipe J, Fricker D, Kopanitsa MV, Duncan RR, Klenerman D, Komiyama NH, Lee SF, Grant SG. Scientific reports. 2016 6:24626. (ICC; Human) [Full Text Article] [PubMed:27109929] [PMC:PMC4842999]
2
Pyrrolidine Dithiocarbamate Prevents Neuroinflammation and Cognitive Dysfunction after Endotoxemia in Rats. Kan MH, Yang T, Fu HQ, Fan L, Wu Y, Terrando N, Wang TL. Frontiers in aging neuroscience. 2016 July;8:175. [Full Text Article] [PubMed:27493629] [PMC:PMC4954850]

Viewing 1-25 of 116 items
DLG4 / PSD95 Antibody - Anti-DLG4 / PSD95 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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Neuroscience
Rabbit Polyclonal (IgG) to Human DLG4 / PSD95
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, IP, WB
Unconjugated
50µg   0.25mg/ml   $485.00
DLG4 / PSD95 Antibody - Anti-PSD95 antibody IHC of human colon, submucosal plexus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 2.5-5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Rabbit Polyclonal to Human DLG4 / PSD95
Zebrafish, Horse, Rat, Rabbit, Mouse, Dog, Guinea pig, Bovine, Human, Monkey
IHC, IHC-P, WB
Unconjugated
100µl   $485.00
Select
Mouse Monoclonal (IgG2a) to Mouse DLG4 / PSD95
Mouse, Bovine, Human
ICC, IF, WB
Unconjugated
25µg   $425.00; 100µg   $545.00
DLG4 / PSD95 Antibody - ICC of PSD95 in cultures of dissociated hippocampal neurons. Cultures were grown and labeled with antibodies against the indicated proteins. A neuron double stained for PSD95.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Mouse Monoclonal [clone 6G6] (IgG2a) to Rat DLG4 / PSD95
Mouse, Bovine, Rat, Human
ICC, IF, IHC, WB
Unconjugated
25µg   1mg/ml   $255.00; 100µg   1mg/ml   $355.00
DLG4 / PSD95 Antibody - ICC of PSD95 in cultures of dissociated hippocampal neurons. Cultures were grown and labeled with antibodies against the indicated proteins. A neuron double stained for PSD95.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Mouse Monoclonal [clone 6G6] (IgG2a,k) to Rat DLG4 / PSD95
Mouse, Bovine, Rat, Human
ICC, IF, IHC, WB
Atto 390 Conjugated
100µg   1mg/ml   $385.00
DLG4 / PSD95 Antibody - ICC of PSD95 in cultures of dissociated hippocampal neurons. Cultures were grown and labeled with antibodies against the indicated proteins. A neuron double stained for PSD95.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Mouse Monoclonal [clone 6G6] (IgG2a,k) to Rat DLG4 / PSD95
Mouse, Bovine, Rat, Human
ICC, IF, IHC, WB
Atto 488 Conjugated
100µg   1mg/ml   $385.00
DLG4 / PSD95 Antibody - ICC of PSD95 in cultures of dissociated hippocampal neurons. Cultures were grown and labeled with antibodies against the indicated proteins. A neuron double stained for PSD95.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Mouse Monoclonal [clone 6G6] (IgG2a,k) to Rat DLG4 / PSD95
Mouse, Bovine, Rat, Human
ICC, IF, IHC, WB
Atto 565 Conjugated
100µg   1mg/ml   $385.00
DLG4 / PSD95 Antibody - ICC of PSD95 in cultures of dissociated hippocampal neurons. Cultures were grown and labeled with antibodies against the indicated proteins. A neuron double stained for PSD95.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Mouse Monoclonal [clone 6G6] (IgG2a,k) to Rat DLG4 / PSD95
Mouse, Bovine, Rat, Human
ICC, IF, IHC, WB
Atto 594 Conjugated
100µg   1mg/ml   $385.00
DLG4 / PSD95 Antibody - ICC of PSD95 in cultures of dissociated hippocampal neurons. Cultures were grown and labeled with antibodies against the indicated proteins. A neuron double stained for PSD95.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Mouse Monoclonal [clone 6G6] (IgG2a,k) to Rat DLG4 / PSD95
Mouse, Bovine, Rat, Human
ICC, IF, IHC, WB
Atto 633 Conjugated
100µg   1mg/ml   $385.00
DLG4 / PSD95 Antibody - ICC of PSD95 in cultures of dissociated hippocampal neurons. Cultures were grown and labeled with antibodies against the indicated proteins. A neuron double stained for PSD95.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Mouse Monoclonal [clone 6G6] (IgG2a,k) to Rat DLG4 / PSD95
Mouse, Bovine, Rat, Human
ICC, IF, IHC, WB
AP Conjugated
100µg   1mg/ml   $375.00
DLG4 / PSD95 Antibody - ICC of PSD95 in cultures of dissociated hippocampal neurons. Cultures were grown and labeled with antibodies against the indicated proteins. A neuron double stained for PSD95.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Mouse Monoclonal [clone 6G6] (IgG2a,k) to Rat DLG4 / PSD95
Mouse, Bovine, Rat, Human
ICC, IF, IHC, WB
Atto 680 Conjugated
100µg   1mg/ml   $385.00
DLG4 / PSD95 Antibody - ICC of PSD95 in cultures of dissociated hippocampal neurons. Cultures were grown and labeled with antibodies against the indicated proteins. A neuron double stained for PSD95.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Mouse Monoclonal [clone 6G6] (IgG2a,k) to Rat DLG4 / PSD95
Mouse, Bovine, Rat, Human
ICC, IF, IHC, WB
Atto 655 Conjugated
100µg   1mg/ml   $385.00
DLG4 / PSD95 Antibody - ICC of PSD95 in cultures of dissociated hippocampal neurons. Cultures were grown and labeled with antibodies against the indicated proteins. A neuron double stained for PSD95.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Mouse Monoclonal [clone 6G6] (IgG2a,k) to Rat DLG4 / PSD95
Mouse, Bovine, Rat, Human
ICC, IF, IHC, WB
APC Conjugated
100µg   1mg/ml   $385.00
DLG4 / PSD95 Antibody - Immunohistochemistry of paraffin-embedded mouse cerebellum using DLG4 antibodyat dilution of 1:100 (40x lens).
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Rabbit Monoclonal to Human DLG4 / PSD95
Mouse, Rat, Human
Flo, IF, IHC, IP, WB
Unconjugated
50µl   $295.00; 100µl   $385.00; 200µl   $560.00
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Mouse Monoclonal [clone 6G6-1C9] (IgG2a) to Mouse DLG4 / PSD95
Mouse, Bovine, Rat
ICC, WB
Unconjugated
100µg   $425.00
DLG4 / PSD95 Antibody - Western blot of PSD-95 antibody
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Rabbit Polyclonal (IgG) to Human DLG4 / PSD95
Mouse, Rat, Human
ELISA, WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $265.00; 200µl   1mg/ml   $335.00
DLG4 / PSD95 Antibody - DLG4 antibody (1 ug/ml) staining of Mouse Brain lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Goat Polyclonal to Human DLG4 / PSD95
Rabbit, Mouse, Dog, Bovine, Rat, Horse, Human, Monkey
Peptide-ELISA, WB
Unconjugated
100µg   0.5mg/ml   $405.00
Select
Mouse Monoclonal (IgG2a,k) to Human DLG4 / PSD95
Rat, Human
ICC, IHC, WB
Unconjugated
100µg   $710.00
DLG4 / PSD95 Antibody - RAT DLG4 Antibody (Ascites) immunohistochemistry of formalin-fixed and paraffin-embedded human brain tissue followed by peroxidase-conjugated secondary antibody and DAB staining. This data demonstrates the use of the RAT DLG4 Antibody (Ascites) for immunohistochemistry.
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Mouse Monoclonal (IgM) to Rat DLG4 / PSD95
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
0.1ml   $325.00
Select
Rabbit Polyclonal (IgG) to Human DLG4 / PSD95
Human
ELISA, WB
Unconjugated
100µg   1mg/ml   $315.00
DLG4 / PSD95 Antibody - Detection of PSD95 in rat neocortex
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Mouse Monoclonal [clone 7E3-1B8] (IgG1) to Mouse DLG4 / PSD95
Mouse, Bovine, Rat
ICC, IF, WB
Unconjugated
100µg   $425.00
DLG4 / PSD95 Antibody - Western blot analysis of tissue lysates using Rabbit Anti-PSD95 Polyclonal Antibody The signal was developed with IRDye TM 800 Conjugated Goat Anti-Rabbit IgG.Predicted Size: 95 KDObserved Size: 90 KD
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Rabbit Monoclonal (IgG) to Human DLG4 / PSD95
WB
Unconjugated
40µg   80µl   0.5mg/ml   $245.00
Select
Mouse Monoclonal [clone 6G6-1C9] (IgG2a) to Rat DLG4 / PSD95
Mouse, Bovine, Rat
WB
Unconjugated
25µg   $355.00; 100µg   1mg/ml   $375.00
Select
Rabbit Polyclonal (IgG) to Human DLG4 / PSD95
Human
ELISA, IF, IHC, IP, WB
Unconjugated
100µg   $335.00
DLG4 / PSD95 Antibody - ICC localization of Psd95 in rat neocortex.
Select
Mouse Monoclonal [clone 7E3] (IgG2a) to Rat DLG4 / PSD95
Mouse, Bovine, Rat, Human
ICC, IF, IHC, WB
Unconjugated
25µg   $255.00; 100µg   $355.00

Viewing 1-25 of 116 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).