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DLC1

deleted in liver cancer 1

Functions as a GTPase-activating protein for the small GTPases RHOA, RHOB, RHOC and CDC42, terminating their downstream signaling. This induces morphological changes and detachment through cytoskeletal reorganization, playing a critical role in biological processes such as cell migration and proliferation. Also functions in vivo as an activator of the phospholipase PLCD1. Active DLC1 increases cell migration velocity but reduces directionality.

Gene Name: deleted in liver cancer 1
Synonyms: DLC1, ARHGAP7, KIAA1723, STARD12, Deleted in liver cancer 1, DLC-1, HP protein, p122-RhoGAP
Target Sequences: NM_182643

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Proteins (4)
Over-Expression Lysate (4)
DLC1 (4)
No (4)
Myc-DDK (Flag) (4)
Human (2)
293T Cells (2)
HEK 293 Cells (2)
DLC1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
122.6 kDa
20 µg/$215
DLC1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
170.4 kDa
20 µg/$150
DLC1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
170.4 kDa
100 µg/$494
DLC1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
122.6 kDa
100 µg/$710
Viewing 1-4 of 4 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).