DLAT / PDC-E2

dihydrolipoamide S-acetyltransferase

DLAT / PDC-E2 is component E2 of the multi-enzyme pyruvate dehydrogenase complex (PDC). PDC resides in the inner mitochondrial membrane and catalyzes the conversion of pyruvate to acetyl coenzyme A. The protein product of this gene, dihydrolipoamide acetyltransferase, accepts acetyl groups formed by the oxidative decarboxylation of pyruvate and transfers them to coenzyme A. Dihydrolipoamide acetyltransferase is the antigen for antimitochondrial antibodies. These autoantibodies are present in nearly 95% of patients with the autoimmune liver disease primary biliary cirrhosis (PBC). In PBC, activated T lymphocytes attack and destroy epithelial cells in the bile duct where this protein is abnormally distributed and overexpressed. PBC enventually leads to cirrhosis and liver failure. Mutations in this gene are also a cause of pyruvate dehydrogenase E2 deficiency which causes primary lactic acidosis in infancy and early childhood.

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Products

ELISA Kits (13)

Type

Competitive EIA (1)

Sandwich (11)

Sandwich CLIA (1)

Target

DLAT / PDC-E2 (13)

Reactivity

Human (1)

Mouse (5)

Rat (1)

Chicken (1)

Guinea pig (1)

Monkey (1)

Porcine (1)

Rabbit (1)

Sheep (1)

Format

12 x 8-Well Microstrips (2)

96-Well Microplate (1)

96-Well Strip Plate (10)

Publications

No (13)

Sample Type

Cell Lysates (1)

Plasma (6)

Serum (6)

Tissue Homogenates (2)

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Mouse DLAT / PDC-E2 (Sandwich ELISA) ELISA Kit - LS-F21360

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

0.16 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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Mouse DLAT / PDC-E2 (Sandwich ELISA) ELISA Kit - LS-F5272

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$782

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Mouse DLAT / PDC-E2 (CLIA) ELISA Kit - LS-F30639

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Mouse

Range:

31.25 - 2000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

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Guinea pig DLAT / PDC-E2 (Sandwich ELISA) ELISA Kit - LS-F43292

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Guinea pig

Range:

3.125 - 200 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

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Monkey DLAT / PDC-E2 (Sandwich ELISA) ELISA Kit - LS-F43294

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

1.563 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

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Porcine DLAT / PDC-E2 (Sandwich ELISA) ELISA Kit - LS-F43295

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Porcine

Range:

1.563 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

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Rabbit DLAT / PDC-E2 (Sandwich ELISA) ELISA Kit - LS-F43296

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rabbit

Range:

15.625 - 1000 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

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Sheep DLAT / PDC-E2 (Sandwich ELISA) ELISA Kit - LS-F43297

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Sheep

Range:

0.781 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$760

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Chicken DLAT / PDC-E2 (Sandwich ELISA) ELISA Kit - LS-F43298

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Chicken

Range:

15.625 - 1000 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

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Human DLAT / PDC-E2 (Sandwich ELISA) ELISA Kit - LS-F37928

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

1.563 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

Select

Mouse DLAT / PDC-E2 (Competitive EIA) ELISA Kit - LS-F28307

Type:

Competitive EIA

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.5 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$913

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Mouse DLAT / PDC-E2 (Sandwich ELISA) ELISA Kit - LS-F32904

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Rat DLAT / PDC-E2 (Sandwich ELISA) ELISA Kit - LS-F38627

Type:

Sandwich

Format:

12 x 8-Well Microstrips

Reactivity:

Rat

Range:

1.563 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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