DKK4

dickkopf WNT signaling pathway inhibitor 4

Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.

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Products

Proteins (6)

Type

Over-Expression Lysate (2)

Recombinant (4)

Target

DKK4 (6)

Publications

No (6)

Tag

6His, N-terminus (1)

GST (1)

His-GST (1)

His-T7 (1)

Myc-DDK (Flag) (2)

Species

Human (4)

Mouse (1)

Source

293T Cells (1)

E. coli (3)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human DKK4 Protein (Recombinant 6His, N-terminus) (Leu19-Leu224) - LS-G26460

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

25 kDa

Price:

10 µg/$265; 50 µg/$315; 100 µg/$365

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Human DKK4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G89962

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

24.88 kDa

Price:

20 µg/$150

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Mouse DKK4 Protein (Recombinant His-GST) (aa37-141) - LS-G16311

Source:

E. coli

Tag:

His-GST

Molecular Weight:

43.5 kDa

Price:

10 µg/$291; 50 µg/$507; 100 µg/$812; 200 µg/$1,010; 1 mg/$2,158; 500 µg/$1,680; 5 mg/$3,543; 2 mg/$2,348

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Human DKK4 Protein (Recombinant GST) (Full Length) - LS-G33263

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

51.3 kDa

Price:

2 µg/$439

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Human DKK4 Protein (Recombinant His-T7) (aa107-212) - LS-G26245

Source:

E. coli

Tag:

His-T7

Molecular Weight:

15.4 kDa

Price:

10 µg/$286; 50 µg/$472; 100 µg/$752; 200 µg/$942; 1 mg/$2,069; 500 µg/$1,600; 5 mg/$3,291; 2 mg/$2,257

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DKK4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G101215

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

24.88 kDa

Price:

100 µg/$494

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