Products
Research Areas
COVID-19
Resources
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us

Locations


Orders Processing,
Shipping & Receiving,
Warehouse

2 Shaker Rd Suites
B001/B101
Shirley, MA 01464


Production Lab

Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036

Telephone Numbers



Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565

Contact Us



Additional Contact Details

Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

DKK1

dickkopf WNT signaling pathway inhibitor 1

Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.

Gene Name: dickkopf WNT signaling pathway inhibitor 1
Synonyms: DKK1, Dickkopf-1 like, DKK-1, Dickkopf-1, Dickkopf-related protein 1, Dickkopf related protein-1, HDkk-1, Hdkk1, Dickkopf-like protein 1, SK
Target Sequences: NM_012242 NP_036374.1 O94907

Publications (7)

1
Dickkopf-1 is oncogenic and involved in invasive growth in non small cell lung cancer. Li S, Qin X, Guo X, Cui A, He Y, Wei S, Wang X, Shan B. PloS one. 2014 8:e84944. (WB; Human) [Full Text Article] [PubMed:24391982] [PMC:PMC3877398] Related Antibodies: LS-C201644.
2
Molecular Characterization of Microtubule Affinity-Regulating Kinase4 from Sus scrofa and Promotion of Lipogenesis in Primary Porcine Placental Trophoblasts. Tian L, Wen A, Dong S, Yan P. International journal of molecular sciences. 2019 March;20:pii E1206. [Full Text Article] [PubMed:30857324] [PMC:PMC6429113] Related Antibodies: LS-B194.
3
Development of a micro-tissue-mediated injectable bone tissue engineering strategy for large segmental bone defect treatment. Wu D, Wang Z, Wang J, Geng Y, Zhang Z, Li Y, Li Q, Zheng Z, Cao Y, Zhang ZY. Stem cell research & therapy. 2018 November;9:331. [Full Text Article] [PubMed:30486863] [PMC:PMC6263540] Related Antibodies: LS-C47394.
4
Differential expression of Dickkopf-1 among non-small cell lung cancer cells. Xiang XJ, Liu YW, Chen DD, Yu S. Molecular medicine reports. 2015 August;12:1935-1940. [Full Text Article] [PubMed:25901391] Related Antibodies: LS-A2867.
5
Maternal obesity stimulates lipotoxicity and up-regulates inflammatory signaling pathways in the full-term swine placenta. Tian Liang, Xie Jinglong, Dong Shusheng, Wen Aiyou. Animal science journal = Nihon chikusan Gakkaiho. 2018 September;89:1310-1322. [Full Text Article] [PubMed:29947166] Related Antibodies: LS-B194.
6
Nitric oxide production upregulates Wnt/ beta -catenin signaling by inhibiting Dickkopf-1. Du Q, Zhang X, Liu Q, Zhang X, Bartels CE, Geller DA. Cancer research. 2013 Nov;73:6526-37. [Full Text Article] [PubMed:24008318] [PMC:PMC3818363] Related Antibodies: LS-A2867.
7
Wnt antagonist DKK1 acts as a tumor suppressor gene that induces apoptosis and inhibits proliferation in human renal cell carcinoma. Hirata H, Hinoda Y, Nakajima K, Kawamoto K, Kikuno N, Ueno K, Yamamura S, Zaman MS, Khatri G, Chen Y, Saini S, Majid S, Deng G, Ishii N, Dahiya R. International journal of cancer. Journal international du cancer. 2011 Apr;128:1793-803. [Full Text Article] [PubMed:20549706] Related Antibodies: LS-A2867.
more

☰ Filters
Products
ELISA Kits (29)
Competitive EIA (2)
Custom (1)
Sandwich (24)
Sandwich CLIA (2)
DKK1 (29)
Human (10)
Mouse (10)
Rat (6)
Chicken (1)
Monkey (1)
Porcine (1)
12 x 8-Well Microstrips (3)
96-Well Microplate (8)
96-Well Strip Plate (18)
No (29)
Cell Culture Supernatants (9)
Cell Lysates (3)
Plasma (26)
Serum (26)
Tissue Homogenates (6)
DKK1 ELISA Kit
Select
Sandwich
96-Well Microplate
Mouse
78.125 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$612
DKK1 ELISA Kit
Select
Sandwich
96-Well Microplate
Mouse
46.9 - 3000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$795
DKK1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Porcine
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$728
DKK1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$764
DKK1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Chicken
3.125 - 200 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
DKK1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
DKK1 ELISA Kit
Select
Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$685
DKK1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$685
DKK1 ELISA Kit
Select
Sandwich
96-Well Microplate
Mouse
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
DKK1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
46.9 - 3000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$717
DKK1 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
DKK1 ELISA Kit
Select
Sandwich
96-Well Microplate
Rat
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
DKK1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$717
DKK1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
46.9 - 3000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$717
DKK1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
DKK1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
DKK1 ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Human
15.625 - 1000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
DKK1 ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Mouse
15.625 - 1000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
DKK1 ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Human
1 - 25 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
DKK1 ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Rat
50 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
DKK1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
100 - 2500 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
DKK1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
DKK1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
46.9 - 3000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum
1 Plate/$795
DKK1 ELISA Kit
Select
Sandwich
96-Well Microplate
Mouse
24.58 - 2400 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$840
DKK1 ELISA Kit
Select
Sandwich
12 x 8-Well Microstrips
Human
63 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum
1 Plate/$618
Viewing 1-25 of 29 product results


Filtered By:
Products: ELISA Kits


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).