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DIRAS3 / ARHI

DIRAS family, GTP-binding RAS-like 3

DIRAS3 / ARHI is a member of the ras superfamily, and is expressed in normal ovarian and breast epithelial cells, but not in ovarian and breast cancers. It is an imprinted gene, with monoallelic expression of the paternal allele, which is associated with growth suppression. Thus, this gene appears to be a putative tumor suppressor gene whose function is abrogated in ovarian and breast cancers.

Gene Name: DIRAS family, GTP-binding RAS-like 3
Family/Subfamily: Ras GTPase superfamily IPR001806 , not assigned-Ras GTPase superfamily IPR001806
Synonyms: DIRAS3, ARHI, GTP-binding protein Di-Ras3, NOEY2, RHOI
Target Sequences: NM_004675 NP_004666.1 O95661

Publications (1)

1
NOEY2 mutations in primary breast cancers and breast hyperplasia. Julun Yang, Aiping Hu, Li Wang, Baolin Li, Yue Chen, Wenxing Zhao, Wenmang Xu, Tao Li. The Breast : official journal of the European Society of Mastology. 2009 Jun;;18:197-203. [Full Text Article] [PubMed:19482475] Related Antibodies: LS-C307871.

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Products
Antibodies (15)
Primary (15)
DIRAS3 / ARHI (15)
Human (15)
Mouse (2)
Rat (2)
IHC (11)
IHC-P (3)
WB (14)
Flo (7)
ELISA (11)
IP (1)
Peptide-ELISA (1)
rabbit (13)
mouse (2)
Product Group
IHCPlus (1)
IgG (12)
IgM,k (1)
monoclonal mc (2)
polyclonal pc (13)
1218 (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
PE Conjugated (1)
Unconjugated (10)
aa1-229 (1)
aa130-230 (1)
No (14)
Yes (1)
DIRAS3 / ARHI Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
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DIRAS3 / ARHI Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
DIRAS3 / ARHI Antibody - DIRAS3 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human brain tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
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DIRAS3 / ARHI Rabbit anti-Human Polyclonal Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
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DIRAS3 / ARHI Mouse anti-Human Monoclonal (aa130-230) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$705
DIRAS3 / ARHI Antibody - Western blot analysis of extracts of various cells.
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DIRAS3 / ARHI Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
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DIRAS3 / ARHI Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
200 µl/$734
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DIRAS3 / ARHI Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, Flo, IHC, WB
Biotin Conjugated
200 µl/$952
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DIRAS3 / ARHI Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, Flo, IHC, WB
FITC Conjugated
200 µl/$952
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DIRAS3 / ARHI Rabbit anti-Human Polyclonal (PE) Antibody
Human
ELISA, Flo, IHC, WB
PE Conjugated
200 µl/$952
Select
DIRAS3 / ARHI Rabbit anti-Human Polyclonal (APC) Antibody
Human
ELISA, Flo, IHC, WB
APC Conjugated
200 µl/$952
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DIRAS3 / ARHI Rabbit anti-Human Polyclonal (Azide-free) (HRP) Antibody
Human
ELISA, Flo, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
DIRAS3 / ARHI Antibody - 1:100 staining human liver carcinoma tissues by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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DIRAS3 / ARHI Rabbit anti-Human Polyclonal Antibody
Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
DIRAS3 / ARHI Antibody - Immunohistochemistry of paraffin-embedded human breast cancer using antibody at 1:100 dilution.
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DIRAS3 / ARHI Rabbit anti-Human Polyclonal (aa1-229) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
DIRAS3 / ARHI Antibody
Select
DIRAS3 / ARHI Mouse anti-Human Monoclonal (1218) Antibody
Human
ELISA, IP, WB
Unconjugated
100 µg/$384
Select
DIRAS3 / ARHI Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
Select
DIRAS3 / ARHI Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
Viewing 1-15 of 15 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).