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20700 44th Avenue W
Lynnwood, WA 98036
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Dipeptidylpeptidase 8 / DPP8
dipeptidyl-peptidase 8
Dipeptidylpeptidase 8 / DPP8 is a member of the peptidase S9B family, a small family of dipeptidyl peptidases that are able to cleave peptide substrates at a prolyl bond. The encoded protein shares similarity with dipeptidyl peptidase IV in that it is ubiquitously expressed, and hydrolyzes the same substrates. These similarities suggest that, like dipeptidyl peptidase IV, this protein may play a role in T-cell activation and immune function. Alternatively spliced transcript variants encoding different isoforms have been described.
| Gene Name: | dipeptidyl-peptidase 8 |
| Family/Subfamily: | Protease , Serine S9B |
| Synonyms: | DPP8, Dipeptidyl-peptidase 8, DPRP1, Dipeptidyl peptidase VIII, Dipeptidylpeptidase 8, DPRP-1, Dipeptidyl peptidase 8, MSTP141, Prolyl dipeptidase DPP8, DP8, DPP VIII |
| Target Sequences: | NM_130434 NP_569118.1 Q6V1X1 |
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