DIABLO / SMAC

diablo, IAP-binding mitochondrial protein

Second mitochondria-derived activator of caspase (SMAC) has been implicated in the activation of apoptosis in response to cell stress. SMAC promotes CASP9 activation by binding to IAPs and removing their inhibitory activity. The inhibitor of apoptosis proteins (IAPs) regulate programmed cell death by inhibiting members of the caspase family of enzymes. Smac/DIABLO is a mitochondrial protein that is released along with cytochrome c during apoptosis and activates cytochrome c/Apaf-1/caspase-9 pathway. Smac is an antagonist of the X-linked inhibitor of apoptosis (XIAP) - the most potent caspase inhibitor of all known inhibitor of apoptosis-family members. Smac promotes apoptosis by eliminating the inhibitory effect of inhibitor-of-apoptosis (IAPs) through physical interactions.

☰ Filters

Products

Proteins (11)

Type

Over-Expression Lysate (5)

Recombinant (6)

Target

DIABLO / SMAC (11)

Publications

No (11)

Tag

6His, N-terminus (1)

GST, N-terminus (1)

His (1)

Myc-DDK (Flag) (7)

Species

Human (8)

Mouse (1)

Source

293T Cells (3)

E. coli (3)

HEK 293 Cells (4)

Wheat Germ Extract (1)

Purification

Purified (1)

Select

Mouse DIABLO / SMAC Protein (Recombinant 6His, N-terminus) (Ala54-Asp237) - LS-G26434

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

21 kDa

Price:

10 µg/$265; 50 µg/$315; 100 µg/$365

Select

Human DIABLO / SMAC Protein (Recombinant GST, N-terminus) (aa119-218) - LS-G62850

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

Select

Human DIABLO / SMAC Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G91169

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

20.7 kDa

Price:

20 µg/$150

Select

Human DIABLO / SMAC Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G91170

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

20.7 kDa

Price:

20 µg/$150

Select

Human DIABLO / SMAC Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G91173

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

21.7 kDa

Price:

20 µg/$150

Select

DIABLO / SMAC Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G107183

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

21.7 kDa

Price:

100 µg/$494

Select

DIABLO / SMAC Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G111355

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

20.7 kDa

Price:

100 µg/$494

Select

Human DIABLO / SMAC Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G72010

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

21.7 kDa

Price:

20 µg/$1,107

Select

Human DIABLO / SMAC Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G72012

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

15.9 kDa

Price:

20 µg/$1,107

Select

Human DIABLO / SMAC Protein (Recombinant His) (Ala56-Asp239) - LS-G97382

Source:

E. coli

Tag:

His

Molecular Weight:

22 kDa

Price:

100 µg/$483

Select

Human DIABLO / SMAC Protein (Recombinant) - LS-G3555

Source:

E. coli

Tag:

None

Price:

100 µg/$411; 500 µg/$985; 20 µg/$276

Viewing 1-11 of 11 product results

(0) Selected Add Selected To Cart Compare Selected Email Selected Clear Selected Top Of Search

---

Filtered By:

Products: Proteins

Clear Filters

If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.