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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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DHCR24 / Seladin-1

24-dehydrocholesterol reductase

DHCR24 / Seladin-1 is a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells.

Gene Name: 24-dehydrocholesterol reductase
Synonyms: DHCR24, DCE, Diminuto/dwarf1 homolog, KIAA0018, Nbla03646, Seladin 1, Seladin-1, SELADIN1, Selective AD indicator 1, Delta(24)-sterol reductase
Target Sequences: NM_014762 NP_055577.1 Q15392

Filtered By: None
Target
DHCR24 / Seladin-1 (24)
Reactivity
Human (24)
Mouse (13)
Rat (11)
Bat (4)
Bovine (8)
Chimpanzee (6)
Dog (4)
Gibbon (6)
Guinea pig (4)
Monkey (8)
Rabbit (4)
Application
IHC (5)
IHC-P (1)
WB (22)
ELISA (4)
Host
rabbit (23)
mouse (1)
Isotype
IgG (21)
Clonality
polyclonal pc (24)
Format
AP Conjugated (1)
APC Conjugated (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (12)
Epitope
aa38-87 (4)
aa431-480 (4)
aa218-246 (1)
aa227-516 (1)
aa57-87 (1)
Publications
No (24)
Showing 1-24 of 24 results

DHCR24 / Seladin-1 Antibody (aa38-87) LS-C80987
Rabbit Polyclonal (IgG) to Human DHCR24 / Seladin-1
Rabbit, Mouse, Bovine, Rat, Human, Monkey
WB
Unconjugated
50µg  $365.00
721_B cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
721_B cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

DHCR24 / Seladin-1 Antibody (aa38-87, HRP) LS-C449244
Rabbit Polyclonal (IgG) to Human DHCR24 / Seladin-1
Rabbit, Mouse, Bovine, Rat, Chimpanzee, Gibbon, Human, Monkey
WB
HRP Conjugated
100µl 0.65mg/ml  $385.00
721_B cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
721_B cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

DHCR24 / Seladin-1 Antibody (aa38-87, Biotin) LS-C449241
Rabbit Polyclonal (IgG) to Human DHCR24 / Seladin-1
Rabbit, Mouse, Bovine, Rat, Chimpanzee, Gibbon, Human, Monkey
WB
Biotin Conjugated
100µl 1mg/ml  $385.00
721_B cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
721_B cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

DHCR24 / Seladin-1 Antibody (aa38-87, FITC) LS-C449243
Rabbit Polyclonal (IgG) to Human DHCR24 / Seladin-1
Rabbit, Mouse, Bovine, Rat, Chimpanzee, Gibbon, Human, Monkey
WB
FITC Conjugated
100µl 1mg/ml  $385.00
721_B cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
721_B cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

DHCR24 / Seladin-1 Antibody (aa218-246) LS-C97331
Rabbit Polyclonal to Human DHCR24 / Seladin-1
Human
WB
Unconjugated
400µl  $305.00
Western blot of anti-DHCR24 Antibody in HepG2 cell line lysates (35 ug/lane). DHCR24 (arrow) was detected using the purified antibody.
Western blot of anti-DHCR24 Antibody in HepG2 cell line lysates (35 ug/lane). DHCR24 (arrow) was detected using the purified antibody.

DHCR24 / Seladin-1 Antibody (aa227-516) LS-C377408
Rabbit Polyclonal (IgG) to Human DHCR24 / Seladin-1
Human
ELISA IHC IHC-P WB
Unconjugated
50µl  $285.00; 100µl  $385.00
Immunohistochemistry of paraffin-embedded human breast cancer using antibody at 1:100 dilution.
Immunohistochemistry of paraffin-embedded human placenta using antibody at 1:100 dilution.
Immunohistochemistry of paraffin-embedded human breast cancer using antibody at 1:100 dilution.
Immunohistochemistry of paraffin-embedded human placenta using antibody at 1:100 dilution.

DHCR24 / Seladin-1 Antibody LS-C753075
Rabbit Polyclonal (IgG) to Human DHCR24 / Seladin-1
Human
ELISA IHC WB
Unconjugated
100µg  $335.00

DHCR24 / Seladin-1 Antibody LS-C402018
Rabbit Polyclonal (IgG) to Human DHCR24 / Seladin-1
Mouse, Rat, Human
ELISA IHC
Unconjugated
20µl  $205.00; 60µl  $235.00; 120µl  $295.00; 200µl  $395.00
Immunohistochemistry of Human thyroid cancer using DHCR24 Polyclonal Antibody at dilution of 1:35.
Immunohistochemistry of Human thyroid cancer using DHCR24 Polyclonal Antibody at dilution of 1:35.
Immunohistochemistry of Human thyroid cancer using DHCR24 Polyclonal Antibody at dilution of 1:35.
Immunohistochemistry of Human thyroid cancer using DHCR24 Polyclonal Antibody at dilution of 1:35.

DHCR24 / Seladin-1 Antibody LS-C334040
Rabbit Polyclonal (IgG) to Human DHCR24 / Seladin-1
Mouse, Human
IHC WB
Unconjugated
50µl  $235.00; 100µl  $315.00; 200µl  $425.00
Western blot analysis of extracts of various cells.
Western blot analysis of extracts of various cells.

DHCR24 / Seladin-1 Antibody LS-C405327
Rabbit Polyclonal (IgG) to Human DHCR24 / Seladin-1
Mouse, Rat, Human
ELISA IHC
Unconjugated
20µl  $205.00; 60µl  $235.00; 120µl  $295.00; 200µl  $395.00
Immunohistochemistry of Human ovarian cancer using DHCR24 Polyclonal Antibody at dilution of 1:40.
Immunohistochemistry of Human ovarian cancer using DHCR24 Polyclonal Antibody at dilution of 1:40.
Immunohistochemistry of Human ovarian cancer using DHCR24 Polyclonal Antibody at dilution of 1:40.
Immunohistochemistry of Human ovarian cancer using DHCR24 Polyclonal Antibody at dilution of 1:40.

DHCR24 / Seladin-1 Antibody LS-C310121
Rabbit Polyclonal (IgG) to Human DHCR24 / Seladin-1
Human
WB
Unconjugated
100µg  $605.00

DHCR24 / Seladin-1 Antibody (HRP) LS-C541790
Rabbit Polyclonal (IgG) to Human DHCR24 / Seladin-1
Human
WB
HRP Conjugated
100µl  $755.00

DHCR24 / Seladin-1 Antibody (Biotin) LS-C521657
Rabbit Polyclonal (IgG) to Human DHCR24 / Seladin-1
Human
WB
Biotin Conjugated
100µl  $755.00

DHCR24 / Seladin-1 Antibody (FITC) LS-C531701
Rabbit Polyclonal (IgG) to Human DHCR24 / Seladin-1
Human
WB
FITC Conjugated
100µl  $755.00

DHCR24 / Seladin-1 Antibody (AP) LS-C503732
Rabbit Polyclonal (IgG) to Human DHCR24 / Seladin-1
Human
WB
AP Conjugated
100µl  $755.00

DHCR24 / Seladin-1 Antibody (PE) LS-C649899
Rabbit Polyclonal (IgG) to Human DHCR24 / Seladin-1
Human
WB
PE Conjugated
100µl  $755.00

DHCR24 / Seladin-1 Antibody (APC) LS-C513442
Rabbit Polyclonal (IgG) to Human DHCR24 / Seladin-1
Human
WB
APC Conjugated
100µl  $755.00

DHCR24 / Seladin-1 Antibody (aa57-87) LS-C97330
Rabbit Polyclonal to Human DHCR24 / Seladin-1
Mouse, Human
WB
Unconjugated
400µl  $305.00
Western blot of anti-DHCR24 Antibody in mouse liver tissue lysates (35 ug/lane). DHCR24 (arrow) was detected using the purified antibody.
Western blot of anti-DHCR24 Antibody in mouse liver tissue lysates (35 ug/lane). DHCR24 (arrow) was detected using the purified antibody.

DHCR24 / Seladin-1 Antibody (aa431-480) LS-C107889
Rabbit Polyclonal (IgG) to Human DHCR24 / Seladin-1
Mouse, Dog, Guinea pig, Bovine, Rat, Bat, Human, Monkey
WB
Unconjugated
50µg  $365.00
DHCR24 / Seladin-1 antibody Western blot of THP-1 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
DHCR24 / Seladin-1 antibody Western blot of THP-1 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

DHCR24 / Seladin-1 Antibody (aa431-480, HRP) LS-C449544
Rabbit Polyclonal (IgG) to Human DHCR24 / Seladin-1
Mouse, Dog, Guinea pig, Bovine, Rat, Bat, Gibbon, Chimpanzee, Human, Monkey
WB
HRP Conjugated
100µl 0.65mg/ml  $385.00
DHCR24 / Seladin-1 antibody Western blot of THP-1 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
DHCR24 / Seladin-1 antibody Western blot of THP-1 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

DHCR24 / Seladin-1 Antibody (aa431-480, Biotin) LS-C449245
Rabbit Polyclonal (IgG) to Human DHCR24 / Seladin-1
Mouse, Dog, Guinea pig, Bovine, Rat, Bat, Gibbon, Chimpanzee, Human, Monkey
WB
Biotin Conjugated
100µl 1mg/ml  $385.00
DHCR24 / Seladin-1 antibody Western blot of THP-1 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
DHCR24 / Seladin-1 antibody Western blot of THP-1 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

DHCR24 / Seladin-1 Antibody (aa431-480, FITC) LS-C449246
Rabbit Polyclonal (IgG) to Human DHCR24 / Seladin-1
Mouse, Dog, Guinea pig, Bovine, Rat, Bat, Gibbon, Chimpanzee, Human, Monkey
WB
FITC Conjugated
100µl 1mg/ml  $385.00
DHCR24 / Seladin-1 antibody Western blot of THP-1 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
DHCR24 / Seladin-1 antibody Western blot of THP-1 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

DHCR24 / Seladin-1 Antibody LS-C482435
Rabbit Polyclonal to Human DHCR24 / Seladin-1
Mouse, Rat, Human
WB
Unconjugated
50µl 1mg/ml  $255.00; 100µl 1mg/ml  $295.00; 200µl 1mg/ml  $375.00
Western blot analysis of Seladin-1 expression in U87 (A); HT29 (B); PC12 (C) whole cell lysates.
Western blot analysis of Seladin-1 expression in U87 (A); HT29 (B); PC12 (C) whole cell lysates.

DHCR24 / Seladin-1 Antibody LS-C307233
Mouse Polyclonal (IgG) to Human DHCR24 / Seladin-1
Human
WB
Unconjugated
50µg  $560.00
Showing 1-24 of 24 results

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PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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