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DGKG
diacylglycerol kinase, gamma 90kDa
DGKG is an enzyme that is a member of the type I subfamily of diacylglycerol kinases, which are involved in lipid metabolism. These enzymes generate phosphatidic acid by catalyzing the phosphorylation of diacylglycerol, a fundamental lipid second messenger that activates numerous proteins, including protein kinase C isoforms, Ras guanyl nucleotide-releasing proteins and some transient receptor potential channels. Diacylglycerol kinase gamma has been implicated in cell cycle regulation and in the negative regulation of macrophage differentiation in leukemia cells. Multiple transcript variants encoding different isoforms have been found for this gene.
| Gene Name: | diacylglycerol kinase, gamma 90kDa |
| Family/Subfamily: | Non-protein kinase , Diacylglycerol kinase |
| Synonyms: | DGKG, DAG kinase gamma, Diacylglycerol kinase gamma, Diacylglyerol kinase gamma, Diglyceride kinase gamma, DGK-GAMMA, DAGK3 |
| Target Sequences: | NM_001346 NP_001337.2 P49619 |
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