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Derlin-3 / DERL3
derlin 3
Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the degradation substrate.
| Gene Name: | derlin 3 |
| Synonyms: | DERL3, C22orf14, Der1-like protein 3, Derlin 3, Derlin-3, DERtrin-3, IZP6, LLN2, DER3, DERtrin 3 |
| Target Sequences: | Q96Q80 Q96Q80 |
Publications (1)
1
Roles for endoplasmic reticulum-associated degradation and the novel endoplasmic reticulum stress response gene Derlin-3 in the ischemic heart. Belmont PJ, Chen WJ, San Pedro MN, Thuerauf DJ, Gellings Lowe N, Gude N, Hilton B, Wolkowicz R, Sussman MA, Glembotski CC. Circulation research. 2010 106:307-16. (WB; Rat)
[PubMed:19940266]
[PMC:PMC3330119]
Related Antibodies: LS-C80661.
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Derlin-3 / DERL3
(17)
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(12)
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(12)
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(6)
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(16)
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(1)
Derlin-3 / DERL3 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
Derlin-3 / DERL3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
Derlin-3 / DERL3 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Chicken, Zebrafish, Pig, Bat, Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Human, Gibbon
WB
HRP Conjugated
100 µl/$469
Derlin-3 / DERL3 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Chicken, Zebrafish, Pig, Bat, Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Human, Gibbon
WB
Biotin Conjugated
100 µl/$469
Derlin-3 / DERL3 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Chicken, Zebrafish, Pig, Bat, Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Human, Gibbon
WB
FITC Conjugated
100 µl/$469
Derlin-3 / DERL3 Rabbit anti-Human Polyclonal (aa71-120) Antibody
Human
WB
Unconjugated
100 µl/$424
Derlin-3 / DERL3 Rabbit anti-Human Polyclonal (aa71-120) (HRP) Antibody
Xenopus, Chicken, Zebrafish, Pig, Horse, Bat, Rat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Orangutan
WB
HRP Conjugated
100 µl/$469
Derlin-3 / DERL3 Rabbit anti-Human Polyclonal (aa71-120) (Biotin) Antibody
Xenopus, Chicken, Zebrafish, Pig, Horse, Bat, Rat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Orangutan
WB
Biotin Conjugated
100 µl/$469
Derlin-3 / DERL3 Rabbit anti-Human Polyclonal (aa71-120) (FITC) Antibody
Xenopus, Chicken, Zebrafish, Pig, Horse, Bat, Rat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Orangutan
WB
FITC Conjugated
100 µl/$469
Derlin-3 / DERL3 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$440; 100 µg/$480
Derlin-3 / DERL3 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, WB
Unconjugated
100 µl/$440; 200 µl/$468
Derlin-3 / DERL3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
293T Cells
Myc-DDK (Flag)
26.5 kDa
20 µg/$150
293T Cells
Myc-DDK (Flag)
23.2 kDa
20 µg/$150
Wheat Germ Extract
GST
49.8 kDa
2 µg/$439
HEK 293 Cells
Myc-DDK (Flag)
26.5 kDa
100 µg/$494
HEK 293 Cells
Myc-DDK (Flag)
23.2 kDa
100 µg/$494
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