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DEPTOR / DEPDC6

DEP domain containing MTOR-interacting protein

Negative regulator of the mTORC1 and mTORC2 signaling pathways. Inhibits the kinase activity of both complexes.

Gene Name:	DEP domain containing MTOR-interacting protein
Synonyms:	DEPTOR, DEP.6, DEPDC6, DEP domain containing 6
Target Sequences:	NM_022783 NP_073620.2 Q8TB45

Publications (1)

SCFFbxo9 and CK2 direct the cellular response to growth factor withdrawal via Tel2/Tti1 degradation and promote survival in multiple myeloma. Fernndez-Siz V, Targosz BS, Lemeer S, Eichner R, Langer C, Bullinger L, Reiter C, Slotta-Huspenina J, Schroeder S, Knorn AM, Kurutz J, Peschel C, Pagano M, Kuster B, Bassermann F. Nature cell biology. 2013 15:72-81. (WB; Human) [PubMed:23263282]

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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