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Guanine nucleotide exchange factor (GEF) activating RAB10. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB10 into its active GTP-bound form. Thereby, stimulates SLC2A4/GLUT4 glucose transporter-enriched vesicles delivery to the plasma membrane in response to insulin.
Gene Name: | DENN/MADD Domain Containing 4C |
Synonyms: | DENND4C, BA513M16.3, C9orf55B, C9orf55, DENN/MADD domain containing 4C |
Target Sequences: | NM_017925 NP_060395.5 Q5VZ89 |
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