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DENND3
DENN/MADD Domain Containing 3
Guanine nucleotide exchange factor (GEF) activating RAB12. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB12 into its active GTP-bound form. Thereby, may play a role in protein transport from recycling endosomes to lysosomes regulating, for instance, the degradation of the transferrin receptor.
| Gene Name: | DENN/MADD Domain Containing 3 |
| Synonyms: | DENND3, KIAA0870, DENN/MADD domain containing 3 |
| Target Sequences: | AB020677 BAA74893.2 A2RUS2 |
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