DENND1C

DENN/MADD Domain Containing 1C

Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1C, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2; see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson, 2010 [PubMed 20154091]).

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Proteins (3)

Type

Over-Expression Lysate (2)

Recombinant (1)

Target

DENND1C (3)

Publications

No (3)

Tag

Myc-DDK (Flag) (3)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (2)

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Human DENND1C Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G84586

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

86.9 kDa

Price:

20 µg/$150

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Human DENND1C Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G69415

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

86.9 kDa

Price:

20 µg/$1,107

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DENND1C Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G109690

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

86.9 kDa

Price:

100 µg/$494

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