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Delta-6 Desaturase / FADS2

fatty acid desaturase 2

Component of a lipid metabolic pathway that catalyzes biosynthesis of highly unsaturated fatty acids (HUFA) from precursor essential polyunsaturated fatty acids (PUFA) linoleic acid (LA) (18:2n-6) and alpha-linolenic acid (ALA) (18:3n-3). Catalyzes the first and rate limiting step in this pathway which is the desaturation of LA (18:2n-6) and ALA (18:3n-3) into gamma-linoleic acid (GLA) (18:3n-6) and stearidonic acid (18:4n-3) respectively and other desaturation steps. Highly unsaturated fatty acids (HUFA) play pivotal roles in many biological functions. It catalizes as well the introduction of a cis double bond in palmitate to produce the mono-unsaturated fatty acid sapienate, the most abundant fatty acid in sebum.

Gene Name: fatty acid desaturase 2
Synonyms: FADS2, D6D, Delta-6 fatty acid desaturase, Delta-6-desaturase, FADSD6, LLCDL2, SLL0262, TU13, Delta(6) desaturase, Delta(6) fatty acid desaturase, Delta-6 desaturase, DES6, Fatty acid desaturase 2
Target Sequences: NM_004265 NP_004256.1 O95864

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Proteins (7)
Over-Expression Lysate (2)
Recombinant (5)
Delta-6 Desaturase / FADS2 (7)
No (7)
6His-SUMO, N-terminus (1)
GST (1)
GST, N-terminus (1)
His-T7 (1)
Myc-DDK (Flag) (3)
Human (6)
293T Cells (1)
E. coli (2)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (2)
Delta-6 Desaturase / FADS2 Protein - 12.5% SDS-PAGE of human FADS2 stained with Coomassie Blue
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Wheat Germ Extract
GST
78.7 kDa
10 µg/$479; 25 µg/$670
Delta-6 Desaturase / FADS2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
52.1 kDa
100 µg/$710
Delta-6 Desaturase / FADS2 Protein - Recombinant Fatty Acid Desaturase 2 By SDS-PAGE
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E. coli
His-T7
18.5 kDa
10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
Delta-6 Desaturase / FADS2 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
6His-SUMO, N-terminus
1 mg/$1,679; 100 µg/$500; 20 µg/$364
Delta-6 Desaturase / FADS2 Protein - Purified recombinant protein FADS2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
52.1 kDa
20 µg/$1,107
Delta-6 Desaturase / FADS2 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
Delta-6 Desaturase / FADS2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
52.1 kDa
20 µg/$215
Viewing 1-7 of 7 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).