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Delta-6 Desaturase / FADS2

fatty acid desaturase 2

Component of a lipid metabolic pathway that catalyzes biosynthesis of highly unsaturated fatty acids (HUFA) from precursor essential polyunsaturated fatty acids (PUFA) linoleic acid (LA) (18:2n-6) and alpha-linolenic acid (ALA) (18:3n-3). Catalyzes the first and rate limiting step in this pathway which is the desaturation of LA (18:2n-6) and ALA (18:3n-3) into gamma-linoleic acid (GLA) (18:3n-6) and stearidonic acid (18:4n-3) respectively and other desaturation steps. Highly unsaturated fatty acids (HUFA) play pivotal roles in many biological functions. It catalizes as well the introduction of a cis double bond in palmitate to produce the mono-unsaturated fatty acid sapienate, the most abundant fatty acid in sebum.

Gene Name: fatty acid desaturase 2
Synonyms: FADS2, D6D, Delta-6 fatty acid desaturase, Delta-6-desaturase, FADSD6, LLCDL2, SLL0262, TU13, Delta(6) desaturase, Delta(6) fatty acid desaturase, Delta-6 desaturase, DES6, Fatty acid desaturase 2
Target Sequences: NM_004265 NP_004256.1 O95864

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Products
Antibodies (29)
Primary (29)
Delta-6 Desaturase / FADS2 (29)
Human (28)
Mouse (9)
Pig (8)
IHC (9)
IHC-P (3)
WB (28)
Flo (15)
ELISA (15)
IF (1)
rabbit (29)
Product Group
IHCPlus (1)
Ig (2)
IgG (15)
polyclonal pc (29)
APC (1)
APC Conjugated (3)
Azide-free (2)
Biotin Conjugated (3)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (3)
Unconjugated (12)
aa1-130 (8)
aa79-108 (7)
aa96-122 (7)
N-Terminus (1)
aa1-131 (1)
No (29)
Delta-6 Desaturase / FADS2 Antibody - Immunohistochemical of paraffin-embedded H.brain section using FADS2 Antibody. Antibody was diluted at 1:25 dilution. A peroxidase-conjugated goat anti-rabbit IgG at 1:400 dilution was used as the secondary antibody, followed by DAB staining.
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Delta-6 Desaturase / FADS2 Rabbit anti-Human Polyclonal (aa96-122) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
Delta-6 Desaturase / FADS2 Antibody - FADS2 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human liver tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
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Delta-6 Desaturase / FADS2 Rabbit anti-Human Polyclonal (aa79-108) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
200 µl/$393
Delta-6 Desaturase / FADS2 Antibody - Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Delta-6 Desaturase / FADS2 Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P
Unconjugated
50 µl/$460
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Delta-6 Desaturase / FADS2 Rabbit anti-Mouse Polyclonal (N-Terminus) Antibody
Mouse
ELISA, WB
Unconjugated
100 µg/$832
Delta-6 Desaturase / FADS2 Antibody - Western blot of Delta-6 Desaturase / FADS2 antibody using recombinant protein encoding amino acids 1-130.
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Delta-6 Desaturase / FADS2 Rabbit anti-Human Polyclonal (aa1-130) Antibody
Pig, Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
Delta-6 Desaturase / FADS2 Antibody - Western blot of Delta-6 Desaturase / FADS2 antibody using recombinant protein encoding amino acids 1-130.
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Delta-6 Desaturase / FADS2 Rabbit anti-Human Polyclonal (aa1-130) (HRP) Antibody
Pig, Human
WB
HRP Conjugated
100 µl/$338; 200 µl/$393; 500 µl/$575; 1 ml/$702; 2 ml/$939; 5 ml/$1,593
Delta-6 Desaturase / FADS2 Antibody - Western blot of Delta-6 Desaturase / FADS2 antibody using recombinant protein encoding amino acids 1-130.
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Delta-6 Desaturase / FADS2 Rabbit anti-Human Polyclonal (aa1-130) (Biotin) Antibody
Pig, Human
WB
Biotin Conjugated
100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596; 2 ml/$824; 5 ml/$1,348
Delta-6 Desaturase / FADS2 Antibody - Western blot of Delta-6 Desaturase / FADS2 antibody using recombinant protein encoding amino acids 1-130.
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Delta-6 Desaturase / FADS2 Rabbit anti-Human Polyclonal (aa1-130) (FITC) Antibody
Pig, Human
WB
FITC Conjugated
100 µl/$348; 200 µl/$407; 500 µl/$605; 1 ml/$755; 2 ml/$993; 5 ml/$1,716
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Delta-6 Desaturase / FADS2 Rabbit anti-Human Polyclonal (aa79-108) Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
200 µl/$734
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Delta-6 Desaturase / FADS2 Rabbit anti-Human Polyclonal (aa79-108) (Biotin) Antibody
Human
ELISA, Flo, IHC, WB
Biotin Conjugated
200 µl/$952
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Delta-6 Desaturase / FADS2 Rabbit anti-Human Polyclonal (aa79-108) (FITC) Antibody
Human
ELISA, Flo, IHC, WB
FITC Conjugated
200 µl/$952
Select
Delta-6 Desaturase / FADS2 Rabbit anti-Human Polyclonal (aa79-108) (APC) Antibody
Human
ELISA, Flo, IHC, WB
APC Conjugated
200 µl/$952
Select
Delta-6 Desaturase / FADS2 Rabbit anti-Human Polyclonal (aa79-108) (PE) Antibody
Human
ELISA, Flo, IHC, WB
PE Conjugated
200 µl/$952
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Delta-6 Desaturase / FADS2 Rabbit anti-Human Polyclonal (aa79-108) (Azide-free) (HRP) Antibody
Human
ELISA, Flo, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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Delta-6 Desaturase / FADS2 Rabbit anti-Human Polyclonal (aa96-122) Antibody
Mouse, Human
ELISA, Flo, WB
Unconjugated
200 µl/$734
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Delta-6 Desaturase / FADS2 Rabbit anti-Human Polyclonal (aa96-122) (Biotin) Antibody
Mouse, Human
ELISA, Flo, WB
Biotin Conjugated
200 µl/$952
Select
Delta-6 Desaturase / FADS2 Rabbit anti-Human Polyclonal (aa96-122) (FITC) Antibody
Mouse, Human
ELISA, Flo, WB
FITC Conjugated
200 µl/$952
Select
Delta-6 Desaturase / FADS2 Rabbit anti-Human Polyclonal (aa96-122) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, Flo, WB
HRP Conjugated, Azide-free
200 µl/$952
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Delta-6 Desaturase / FADS2 Rabbit anti-Human Polyclonal (aa96-122) (PE) Antibody
Mouse, Human
ELISA, Flo, WB
PE Conjugated
200 µl/$952
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Delta-6 Desaturase / FADS2 Rabbit anti-Human Polyclonal (aa96-122) (APC) Antibody
Mouse, Human
ELISA, Flo, WB
APC Conjugated
200 µl/$952
Delta-6 Desaturase / FADS2 Antibody - Anti-FADS2 Antibody at 1:2000 dilution + Human liver lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size: 52 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Delta-6 Desaturase / FADS2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Flo, WB
Unconjugated
200 µl/$393
Delta-6 Desaturase / FADS2 Antibody - Anti-FADS2 Antibody at 1:2000 dilution + Human liver lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size: 52 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Select
Delta-6 Desaturase / FADS2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
200 µl/$393
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Delta-6 Desaturase / FADS2 Rabbit anti-Human Polyclonal (aa1-131) Antibody
Mouse, Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
Delta-6 Desaturase / FADS2 Antibody
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Delta-6 Desaturase / FADS2 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µl/$286; 100 µl/$321
Delta-6 Desaturase / FADS2 Antibody - Western blot analysis of extracts of various cell lines, using FADS2 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 3s.
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Delta-6 Desaturase / FADS2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).