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DEFB107A
Defensin, beta 107
Defensins form a family of antimicrobial and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. Chromosome 8p23 contains at least two copies of the duplicated beta-defensin cluster. This duplication results in two identical copies of defensin, beta 107, DEFB107A and DEFB107B, in tail-to-tail orientation. This gene, DEFB107A, represents the more centromeric copy.
| Gene Name: | Defensin, beta 107 |
| Synonyms: | DEFB107A, Beta-defensin 7, BD-7, DEFB-7, Defensin, beta 107A, Defensin, beta 7, DEFB107, DEFB7, Beta-defensin 107, Defensin, beta 107 |
| Target Sequences: | NP_001032757.2 Q8IZN7 |
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