LSBio
LSBio
Products
Services
Research Areas
Resources
Contact Us
Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone: 866-819-4732 (Toll Free North America)
206-374-1102 (International)

Fax: 866-206-6909 (Toll Free North America)
206-577-4565 (International)

How to Buy - Details about how to buy our products.

Orders@LSBio.com - To submit a new order.

Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues.

Technical.Support@LSBio.com - To request technical information requests about an LSBio product or its application.

Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.
Products
Services
Research Areas
Resources
Contact Us

DEFA5 / Defensin 5

defensin, alpha 5, Paneth cell-specific

Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several of the alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 5, is highly expressed in the secretory granules of Paneth cells of the ileum.

Gene Name: defensin, alpha 5, Paneth cell-specific
Synonyms: DEFA5, DEF5, Defensin, alpha 5, Defensin 5, Defensin-5, HD-5, HD5(20-94)
Target Sequences: NM_021010 NP_066290.1 Q01523

Publications (5)

1
Human defensin 5 expression in intestinal metaplasia of the upper gastrointestinal tract. Shen B, Porter EM, Reynoso E, Shen C, Ghosh D, Connor JT, Drazba J, Rho HK, Gramlich TL, Li R, Ormsby AH, Sy MS, Ganz T, Bevins CL. Journal of clinical pathology. 2005 58:687-94. [PubMed:15976333] [PMC:PMC1770712]
2
Reduced Paneth cell alpha-defensins in ileal Crohn's disease. Wehkamp J, Salzman NH, Porter E, Nuding S, Weichenthal M, Petras RE, Shen B, Schaeffeler E, Schwab M, Linzmeier R, Feathers RW, Chu H, Lima H, Fellermann K, Ganz T, Stange EF, Bevins CL. Proceedings of the National Academy of Sciences of the United States of America. 2005 102:18129-34. (IHC, WB) [PubMed:16330776] [PMC:PMC1306791]
3
Paneth cell antimicrobial peptides: topographical distribution and quantification in human gastrointestinal tissues. Wehkamp J, Chu H, Shen B, Feathers RW, Kays RJ, Lee SK, Bevins CL. FEBS letters. 2006 580:5344-50. (ICC, IHC) [PubMed:16989824]
4
Lowered expression of galectin-2 is associated with lymph node metastasis in gastric cancer. Jung JH, Kim HJ, Yeom J, Yoo C, Shin J, Yoo J, Kang CS, Lee C. Journal of gastroenterology. 2012 47:37-48. (WB; Human) [PubMed:22015694]
5
Profiling of differentially expressed proteins in stage IV colorectal cancers with good and poor outcomes. Kim HJ, Kang UB, Lee H, Jung JH, Lee ST, Yu MH, Kim H, Lee C. Journal of proteomics. 2012 75:2983-97. [PubMed:22178445]
more

Filtered by: None
Target
DEFA5 / Defensin 5 (50)
Reactivity
Human (43)
Mouse (4)
Rabbit (3)
Application
IHC (32)
IHC-Fr (7)
IHC-P (12)
WB (43)
Flo (4)
ELISA (12)
ICC (10)
IF (6)
IP (8)
RIA (1)
Host
rabbit (26)
mouse (24)
Isotype
IgG (27)
IgG2a (4)
IgG2b (9)
Clonality
monoclonal mc (24)
polyclonal pc (26)
Clone
8C8 (6)
R3 (3)
Format
AP Conjugated (1)
APC (2)
APC Conjugated (3)
Biotin Conjugated (6)
Cy3 Conjugated (2)
Cy7 Conjugated (2)
DY488 Conjugated (1)
DY550 Conjugated (1)
DY650 Conjugated (1)
FITC Conjugated (7)
HRP Conjugated (5)
PE Conjugated (3)
Unconjugated (18)
Epitope
aa20-94 (20)
C-Terminus (4)
Publications
No (50)
Showing 1-25 of 50 results

DEFA5 / Defensin 5 Antibody (clone 8C8) IHC-plus™ LS-B2904
Mouse Monoclonal [clone 8C8] to Human DEFA5 / Defensin 5
Human
IF IHC IHC-P WB
Unconjugated
100µl 2.35mg/ml  $425.00
Anti-DEFA5 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

DEFA5 / Defensin 5 Antibody (clone 8C8, Biotin) LS-C141649
Mouse Monoclonal [clone 8C8] (IgG2b) to Human DEFA5 / Defensin 5
Human
IF IHC IHC-P WB
Biotin Conjugated
100µl  $365.00
Anti-DEFA5 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human skeletal muscle myocytes showing moderate nuclear and faint cytoplasmic staining.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

DEFA5 / Defensin 5 Antibody (clone 8C8, DY650) LS-C141650
Mouse Monoclonal [clone 8C8] (IgG2b) to Human DEFA5 / Defensin 5
Human
IF IHC IHC-P WB
DY650 Conjugated
100µl  $365.00
Anti-DEFA5 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human skeletal muscle myocytes showing moderate nuclear and faint cytoplasmic staining.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

DEFA5 / Defensin 5 Antibody (clone 8C8, DY488) LS-C141651
Mouse Monoclonal [clone 8C8] (IgG2b) to Human DEFA5 / Defensin 5
Human
IF IHC IHC-P WB
DY488 Conjugated
100µl  $365.00
Anti-DEFA5 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human skeletal muscle myocytes showing moderate nuclear and faint cytoplasmic staining.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

DEFA5 / Defensin 5 Antibody (clone 8C8, DY550) LS-C141653
Mouse Monoclonal [clone 8C8] (IgG2b) to Human DEFA5 / Defensin 5
Human
IF IHC IHC-P WB
DY550 Conjugated
100µl  $365.00
Anti-DEFA5 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human skeletal muscle myocytes showing moderate nuclear and faint cytoplasmic staining.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

DEFA5 / Defensin 5 Antibody (C-Terminus) LS-C37786
Rabbit Polyclonal (IgG) to Human DEFA5 / Defensin 5
Human
ELISA WB
Unconjugated
100µg 100µl  $710.00

DEFA5 / Defensin 5 Antibody IHC-plus™ LS-B3145
Mouse Monoclonal (IgG2b) to Human DEFA5 / Defensin 5
Human
IF IHC IHC-P WB
Unconjugated
50µl 2.35mg/ml  $425.00
Anti-DEFA5 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

DEFA5 / Defensin 5 Antibody LS-C50934
Mouse Monoclonal (IgG2a) to Rabbit DEFA5 / Defensin 5
Rabbit
Flo IHC IHC-Fr IHC-P WB
Unconjugated
100µg  $950.00

DEFA5 / Defensin 5 Antibody (C-Terminus) LS-C37785
Rabbit Polyclonal (IgG) to Human DEFA5 / Defensin 5
Human
ELISA WB
Unconjugated
100µl  $725.00

DEFA5 / Defensin 5 Antibody (clone R3) LS-C131098
Mouse Monoclonal [clone R3] (IgG2a) to Rabbit DEFA5 / Defensin 5
Rabbit
ELISA Flo IHC IHC-Fr IHC-P WB
Unconjugated
100µg  $1,290.00

DEFA5 / Defensin 5 Antibody (clone R3) LS-C202059
Mouse Monoclonal [clone R3] (IgG2a) to Human DEFA5 / Defensin 5
Human
Flo IHC IHC-Fr IHC-P WB
Unconjugated
100µg  $935.00

DEFA5 / Defensin 5 Antibody (aa20-94) LS-C314262
Mouse Monoclonal (IgG) to Human DEFA5 / Defensin 5
Human
ICC IHC IP WB
Unconjugated
20µl 1mg/ml  $205.00; 100µl 1mg/ml  $255.00; 200µl 1mg/ml  $355.00; 1ml 1mg/ml  $530.00; 10ml 1mg/ml  $2,100.00
Western blot of recombinant DEFA5 / Defensin 5.

DEFA5 / Defensin 5 Antibody (aa20-94) LS-C124300
Mouse Monoclonal (IgG2b) to Human DEFA5 / Defensin 5
Human
ELISA IHC IHC-Fr IHC-P WB
Unconjugated
100µg  $950.00

DEFA5 / Defensin 5 Antibody (clone R3) LS-C140190
Mouse Monoclonal [clone R3] (IgG2a) to Rabbit DEFA5 / Defensin 5
Rabbit
Flo IHC IHC-Fr IHC-P WB
Unconjugated
100µg  $635.00

DEFA5 / Defensin 5 Antibody LS-C663071
Mouse Monoclonal (IgG2b) to Human DEFA5 / Defensin 5
Human
IHC IHC-Fr RIA WB
Unconjugated
0.5mg  $1,980.00

DEFA5 / Defensin 5 Antibody (aa20-94, Biotin) LS-C686487
Mouse Monoclonal (IgG) to Human DEFA5 / Defensin 5
Human
ICC IHC IP WB
Biotin Conjugated
100µl 1mg/ml  $265.00; 200µl 1mg/ml  $315.00; 1ml 1mg/ml  $575.00; 10ml 1mg/ml  $2,310.00
Western blot of recombinant DEFA5 / Defensin 5.

DEFA5 / Defensin 5 Antibody (aa20-94, FITC) LS-C693177
Mouse Monoclonal (IgG) to Human DEFA5 / Defensin 5
Human
ICC IHC IP WB
FITC Conjugated
100µl 1mg/ml  $275.00; 200µl 1mg/ml  $325.00; 1ml 1mg/ml  $635.00; 10ml 1mg/ml  $2,520.00
Western blot of recombinant DEFA5 / Defensin 5.

DEFA5 / Defensin 5 Antibody (aa20-94, Cy3) LS-C701572
Mouse Monoclonal (IgG) to Human DEFA5 / Defensin 5
Human
ICC IHC IP WB
Cy3 Conjugated
100µl 1mg/ml  $355.00; 200µl 1mg/ml  $445.00; 1ml 1mg/ml  $1,050.00; 10ml 1mg/ml  $4,215.00
Western blot of recombinant DEFA5 / Defensin 5.

DEFA5 / Defensin 5 Antibody (aa20-94, HRP) LS-C710597
Mouse Monoclonal (IgG) to Human DEFA5 / Defensin 5
Human
ICC IHC IP WB
HRP Conjugated
100µl 1mg/ml  $285.00; 200µl 1mg/ml  $345.00; 1ml 1mg/ml  $680.00; 10ml 1mg/ml  $2,745.00
Western blot of recombinant DEFA5 / Defensin 5.

DEFA5 / Defensin 5 Antibody (aa20-94, PE) LS-C724658
Mouse Monoclonal (IgG) to Human DEFA5 / Defensin 5
Human
ICC IHC IP WB
PE Conjugated
100µl  $275.00; 200µl  $325.00; 1ml  $635.00; 10ml  $2,520.00
Western blot of recombinant DEFA5 / Defensin 5.

DEFA5 / Defensin 5 Antibody (aa20-94, APC, Cy7) LS-C733645
Mouse Monoclonal (IgG) to Human DEFA5 / Defensin 5
Human
ICC IHC IP WB
APC, Cy7 Conjugated
100µl  $455.00; 200µl  $635.00; 1ml  $1,575.00; 10ml  $6,330.00
Western blot of recombinant DEFA5 / Defensin 5.

DEFA5 / Defensin 5 Antibody (aa20-94, APC) LS-C740116
Mouse Monoclonal (IgG) to Human DEFA5 / Defensin 5
Human
ICC IHC IP WB
APC Conjugated
100µl  $305.00; 200µl  $375.00; 1ml  $785.00; 10ml  $2,490.00
Western blot of recombinant DEFA5 / Defensin 5.

DEFA5 / Defensin 5 Antibody (clone 8C8) LS-C140136
Mouse Monoclonal [clone 8C8] (IgG2b) to Human DEFA5 / Defensin 5
Human
IHC IHC-Fr WB
Unconjugated
100µg  $635.00

DEFA5 / Defensin 5 Antibody LS-C121267
Mouse Monoclonal (IgG2b) to Human DEFA5 / Defensin 5
Human
IHC IHC-P
Unconjugated
100µl  $605.00

DEFA5 / Defensin 5 Antibody LS-C402972
Rabbit Polyclonal (IgG) to Human DEFA5 / Defensin 5
Human
ELISA IHC
Unconjugated
20µl 0.2mg/ml  $205.00; 60µl 0.2mg/ml  $235.00; 120µl 0.2mg/ml  $295.00; 200µl 0.2mg/ml  $395.00
Immunohistochemistry of paraffin-embedded Human thyroid cancer using DEFA5 Polyclonal Antibody at dilution of 1:15.
Immunohistochemistry of paraffin-embedded Human thyroid cancer using DEFA5 Polyclonal Antibody at dilution of 1:15.
Showing 1-25 of 50 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

Get Social With Us!
Follow us on Facebook Follow us on Google+ Follow us on LinkedIn PSL Alliance Member
Copyright © 2019 LifeSpan BioSciences, Inc. All Rights Reserved Privacy Policy