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DEFA3 / Defensin Alpha 3

defensin, alpha 3, neutrophil-specific

Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 3, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 1 by only one amino acid. This gene and the gene encoding defensin, alpha 1 are both subject to copy number variation.

Gene Name: defensin, alpha 3, neutrophil-specific
Synonyms: DEFA3, DEF3, HNP-3, HP-3, HNP3, Neutrophil defensin 3, HP3, Neutrophil peptide 3, Defensin, alpha 3
Target Sequences: NM_005217 NP_005208.1 P59666

☰ Filters
Products
Antibodies (29)
Primary (29)
DEFA3 / Defensin Alpha 3 (29)
Human (29)
IHC (6)
IHC-P (2)
WB (25)
ELISA (8)
Peptide-ELISA (2)
rabbit (29)
IgG (11)
polyclonal pc (29)
APC (2)
APC Conjugated (3)
Azide-free (1)
Biotin Conjugated (3)
Cy3 Conjugated (2)
Cy7 Conjugated (2)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (3)
Unconjugated (10)
aa20-94 (8)
aa21-94 (8)
aa38-65 (7)
Internal (1)
Ser52 (1)
aa3-52 (1)
No (29)
DEFA3 / Defensin Alpha 3 Antibody - 1:100 staining mouse kidney tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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DEFA3 / Defensin Alpha 3 Rabbit anti-Human Polyclonal Antibody
Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
DEFA3 / Defensin Alpha 3 Antibody - Western blot of recombinant DEFA3.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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DEFA3 / Defensin Alpha 3 Rabbit anti-Human Polyclonal (aa20-94) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
DEFA3 / Defensin Alpha 3 Antibody - Western blot of recombinant DEFA3.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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DEFA3 / Defensin Alpha 3 Rabbit anti-Human Polyclonal (aa20-94) (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$338; 200 µl/$393; 500 µl/$575; 1 ml/$702; 2 ml/$939; 5 ml/$1,593
DEFA3 / Defensin Alpha 3 Antibody - Western blot of recombinant DEFA3.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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DEFA3 / Defensin Alpha 3 Rabbit anti-Human Polyclonal (aa20-94) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596; 2 ml/$824; 5 ml/$1,348
DEFA3 / Defensin Alpha 3 Antibody - Western blot of recombinant DEFA3.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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DEFA3 / Defensin Alpha 3 Rabbit anti-Human Polyclonal (aa20-94) (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$348; 200 µl/$407; 500 µl/$605; 1 ml/$755; 2 ml/$993; 5 ml/$1,716
DEFA3 / Defensin Alpha 3 Antibody - Western blot of recombinant DEFA3.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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DEFA3 / Defensin Alpha 3 Rabbit anti-Human Polyclonal (aa20-94) (PE) Antibody
Human
WB
PE Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
DEFA3 / Defensin Alpha 3 Antibody - Western blot of recombinant DEFA3.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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DEFA3 / Defensin Alpha 3 Rabbit anti-Human Polyclonal (aa20-94) (APC) Antibody
Human
WB
APC Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
DEFA3 / Defensin Alpha 3 Antibody - Immunohistochemistry of paraffin-embedded human skeletal muscle tissue at dilution 1:100
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DEFA3 / Defensin Alpha 3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
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DEFA3 / Defensin Alpha 3 Rabbit anti-Human Polyclonal (Internal) Antibody
Human
ELISA, IHC
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
DEFA3 / Defensin Alpha 3 Antibody - Western blot analysis of extracts of various cells.
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DEFA3 / Defensin Alpha 3 Rabbit anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
DEFA3 / Defensin Alpha 3 Antibody - Immunohistochemistry analysis of Defensin α3 antibody in paraffin-embedded human skeletal muscle tissue.
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DEFA3 / Defensin Alpha 3 Rabbit anti-Human Polyclonal (aa3-52) Antibody
Human
IHC, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
DEFA3 / Defensin Alpha 3 Antibody - IHC of Defensin 3 (S52) pAb in paraffin-embedded human skeletal muscle tissue.
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DEFA3 / Defensin Alpha 3 Rabbit anti-Human Polyclonal (Ser52) Antibody
Human
IHC, IHC-P
Unconjugated
50 µl/$321; 100 µl/$403
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DEFA3 / Defensin Alpha 3 Rabbit anti-Human Polyclonal (aa38-65) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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DEFA3 / Defensin Alpha 3 Rabbit anti-Human Polyclonal (aa38-65) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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DEFA3 / Defensin Alpha 3 Rabbit anti-Human Polyclonal (aa38-65) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
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DEFA3 / Defensin Alpha 3 Rabbit anti-Human Polyclonal (aa38-65) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
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DEFA3 / Defensin Alpha 3 Rabbit anti-Human Polyclonal (aa38-65) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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DEFA3 / Defensin Alpha 3 Rabbit anti-Human Polyclonal (aa38-65) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
DEFA3 / Defensin Alpha 3 Antibody - DEFA3 Antibody western blot of Jurkat cell line lysates (35 ug/lane). The DEFA3 antibody detected the DEFA3 protein (arrow).
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DEFA3 / Defensin Alpha 3 Rabbit anti-Human Polyclonal (aa38-65) Antibody
Human
WB
Unconjugated
400 µl/$393
DEFA3 / Defensin Alpha 3 Antibody - Western Blot; Sample: Recombinant DEFa3, Human.
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DEFA3 / Defensin Alpha 3 Rabbit anti-Human Polyclonal (aa21-94) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
DEFA3 / Defensin Alpha 3 Antibody - Western Blot; Sample: Recombinant DEFa3, Human.
Select
DEFA3 / Defensin Alpha 3 Rabbit anti-Human Polyclonal (aa21-94) (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$338; 200 µl/$393; 500 µl/$575; 1 ml/$702; 2 ml/$939; 5 ml/$1,593
DEFA3 / Defensin Alpha 3 Antibody - Western Blot; Sample: Recombinant DEFa3, Human.
Select
DEFA3 / Defensin Alpha 3 Rabbit anti-Human Polyclonal (aa21-94) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596; 2 ml/$824; 5 ml/$1,348
DEFA3 / Defensin Alpha 3 Antibody - Western Blot; Sample: Recombinant DEFa3, Human.
Select
DEFA3 / Defensin Alpha 3 Rabbit anti-Human Polyclonal (aa21-94) (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$348; 200 µl/$407; 500 µl/$605; 1 ml/$755; 2 ml/$993; 5 ml/$1,716
DEFA3 / Defensin Alpha 3 Antibody - Western Blot; Sample: Recombinant DEFa3, Human.
Select
DEFA3 / Defensin Alpha 3 Rabbit anti-Human Polyclonal (aa21-94) (APC) Antibody
Human
WB
APC Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
DEFA3 / Defensin Alpha 3 Antibody - Western Blot; Sample: Recombinant DEFa3, Human.
Select
DEFA3 / Defensin Alpha 3 Rabbit anti-Human Polyclonal (aa21-94) (PE) Antibody
Human
WB
PE Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).