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DEFA1 / Defensin Alpha 1

defensin, alpha 1

Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 3 by only one amino acid. This gene and the gene encoding defensin, alpha 3 are both subject to copy number variation.

Gene Name: defensin, alpha 1
Synonyms: DEFA1, DEFA2, Defensin, alpha 2, HP-1, HP1, Myeloid-related sequence, MRS, DEF1, Defensin, alpha 1, HNP-1, Neutrophil defensin 1
Target Sequences: NM_004084 NP_004075.1 P59665

☰ Filters
Products
Proteins (12)
Over-Expression Lysate (2)
Recombinant (10)
DEFA1 / Defensin Alpha 1 (12)
No (12)
GST (1)
GST, N-terminus (2)
GST-6His, N-terminus (1)
His (1)
His-GST (2)
Myc-DDK (Flag) (3)
Human (8)
Mouse (3)
293T Cells (1)
E. coli (6)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Yeast (1)
Purified (7)
Low endotoxin level (1)
Biologically active (2)
DEFA1 / Defensin Alpha 1 Protein - Recombinant Defensin Alpha 1, Neutrophil By SDS-PAGE
Select
E. coli
His
9.8 kDa
10 µg/$291; 50 µg/$502; 100 µg/$802; 200 µg/$1,002; 1 mg/$2,144; 500 µg/$1,668; 5 mg/$3,501; 2 mg/$2,334
DEFA1 / Defensin Alpha 1 Protein - Recombinant Defensin Alpha 1, Neutrophil By SDS-PAGE
Select
E. coli
His-GST
38.3 kDa
10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
DEFA1 / Defensin Alpha 1 Protein - Recombinant  Defensin Alpha 2 By SDS-PAGE
Select
E. coli
His-GST
38.4 kDa
10 µg/$279; 50 µg/$427; 100 µg/$682; 200 µg/$852; 1 mg/$1,950; 500 µg/$1,494; 5 mg/$2,983; 2 mg/$2,136
DEFA1 / Defensin Alpha 1 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
E. coli
GST-6His, N-terminus
34.1 kDa
1 mg/$1,679; 100 µg/$598; 20 µg/$405
DEFA1 / Defensin Alpha 1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
10 kDa
20 µg/$150
DEFA1 / Defensin Alpha 1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
10 kDa
100 µg/$494
DEFA1 / Defensin Alpha 1 Protein - 12.5% SDS-PAGE of human DEFA1 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
36.08 kDa
10 µg/$479; 25 µg/$670
Select
None
Biologically active
3.4 kD
20 µg/$484
DEFA1 / Defensin Alpha 1 Protein - Purified recombinant protein DEFA1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
10 kDa
20 µg/$1,107
DEFA1 / Defensin Alpha 1 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
Yeast
GST, N-terminus
100 µg/$570; 20 µg/$395; 1 mg/$1,973
DEFA1 / Defensin Alpha 1 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
E. coli
GST, N-terminus
1 mg/$1,679; 100 µg/$500; 20 µg/$364
Select
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
3.4 kDa
5 µg/$268; 20 µg/$349
Viewing 1-12 of 12 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).