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DECR2
2,4-dienoyl CoA reductase 2, peroxisomal
Auxiliary enzyme of beta-oxidation. Participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. Has activity towards short and medium chain 2,4-dienoyl-CoAs, but also towards 2,4,7,10,13,16,19-docosaheptaenoyl-CoA, suggesting that it does not constitute a rate limiting step in the peroxisomal degradation of docosahexaenoic acid.
| Gene Name: | 2,4-dienoyl CoA reductase 2, peroxisomal |
| Synonyms: | DECR2, 2,4-dienoyl-CoA reductase 2, PDCR, SDR17C1 |
| Target Sequences: | NM_020664 NP_065715.1 Q9NUI1 |
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