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DDX42

DEAD (Asp-Glu-Ala-Asp) box helicase 42

ATP-dependent RNA helicase. Binds to partially double-stranded RNAs (dsRNAs) in order to unwind RNA secondary structures. Unwinding is promoted in the presence of single-strand binding proteins. Mediates also RNA duplex formation thereby displacing the single-strand RNA binding protein. ATP and ADP modulate its activity: ATP binding and hydrolysis by DDX42 triggers RNA strand separation, whereas the ADP-bound form of the protein triggers annealing of complementary RNA strands. Involved in the survival of cells by interacting with TP53BP2 and thereby counteracting the apoptosis-stimulating activity of TP53BP2. Relocalizes TP53BP2 to the cytoplasm.

Gene Name: DEAD (Asp-Glu-Ala-Asp) box helicase 42
Family/Subfamily: DEAD box protein
Synonyms: DDX42, DEAD box protein 42, RNAHP, RNA helicase-like protein, SF3b125, RNA helicase-related protein, SF3b125 DEAD-box protein, RHELP, SF3b DEAD box protein
Target Sequences: NM_007372 NP_031398.2 Q86XP3

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Products
Antibodies (14)
Primary (14)
DDX42 (14)
Human (14)
Mouse (4)
IHC (5)
IHC-P (1)
WB (10)
ELISA (5)
IF (1)
IP (2)
Peptide-ELISA (2)
rabbit (13)
mouse (1)
IgG (8)
polyclonal pc (14)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
Unconjugated (8)
C-Terminus (4)
aa104-138 (1)
aa800-850 (1)
aa888-938 (1)
No (14)
DDX42 Antibody - Immunohistochemistry of paraffin-embedded human tonsil using antibody at dilution of 1:100.
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DDX42 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
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DDX42 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IHC
HRP Conjugated
50 µg/$294; 100 µg/$360
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DDX42 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, IHC
Biotin Conjugated
50 µg/$294; 100 µg/$360
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DDX42 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, IHC
FITC Conjugated
50 µg/$294; 100 µg/$360
DDX42 Antibody - 1:100 staining mouse muscle tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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DDX42 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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DDX42 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
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DDX42 Mouse anti-Human Polyclonal Antibody
Human
IF, WB
Unconjugated
50 µg/$705
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DDX42 Rabbit anti-Human Polyclonal (aa888-938) Antibody
Mouse, Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
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DDX42 Rabbit anti-Human Polyclonal (aa800-850) Antibody
Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
DDX42 Antibody - All lanes: Anti-DDX42 Antibody (N-Term) at 1:2000 dilution. Lane 1: A431 whole cell lysate. Lane 2: HeLa whole cell lysate. Lane 3: Jurkat whole cell lysate. Lane 4: K562 whole cell lysate. Lane 5: NIH/3T3 whole cell lysate Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1:10000 dilution. Predicted band size: 103 kDa. Blocking/Dilution buffer: 5% NFDM/TBST.
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DDX42 Rabbit anti-Human Polyclonal (aa104-138) Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
200 µl/$393
DDX42 Antibody - Western blot of DDX42 Antibody with human MCF7 Whole Cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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DDX42 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
DDX42 Antibody - Western blot of DDX42 Antibody with human MCF7 Whole Cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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DDX42 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$469
DDX42 Antibody - Western blot of DDX42 Antibody with human MCF7 Whole Cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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DDX42 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$469
DDX42 Antibody - Western blot of DDX42 Antibody with human MCF7 Whole Cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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DDX42 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$469
Viewing 1-14 of 14 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).