DDX1

DEAD (Asp-Glu-Ala-Asp) box helicase 1

Acts as an ATP-dependent RNA helicase, able to unwind both RNA-RNA and RNA-DNA duplexes. Possesses 5' single-stranded RNA overhang nuclease activity. Possesses ATPase activity on various RNA, but not DNA polynucleotides. May play a role in RNA clearance at DNA double-strand breaks (DSBs), thereby facilitating the template-guided repair of transcriptionally active regions of the genome. Together with RELA, acts as a coactivator to enhance NF-kappa-B-mediated transcriptional activation. Acts as a positive transcriptional regulator of cyclin CCND2 expression. Binds to the cyclin CCND2 promoter region. Associates with chromatin at the NF-kappa-B promoter region via association with RELA. Binds to poly(A) RNA. May be involved in 3'-end cleavage and polyadenylation of pre-mRNAs. Component of the tRNA-splicing ligase complex required to facilitate the enzymatic turnover of catalytic subunit RTCB: together with archease (ZBTB8OS), acts by facilitating the guanylylation of RTCB, a key intermediate step in tRNA ligation (PubMed:24870230). Required for HIV-1 Rev function as well as for HIV-1 replication. Binds to the RRE sequence of HIV-1 mRNAs.

☰ Filters

Products

Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

DDX1 (5)

Publications

No (5)

Tag

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (3)

Species

Human (4)

Source

293T Cells (1)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (1)

Select

DDX1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G116303

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

82.3 kDa

Price:

100 µg/$494

Select

Human DDX1 Protein (Recombinant GST) (Full Length) - LS-G28181

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

107.14 kDa

Price:

10 µg/$479; 25 µg/$670

Select

Human DDX1 Protein (Recombinant GST, N-terminus) (aa642-740) - LS-G58316

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

Select

Human DDX1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G69191

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

82.3 kDa

Price:

20 µg/$1,107

Select

Human DDX1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G84037

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

82.3 kDa

Price:

20 µg/$150

Viewing 1-5 of 5 product results

(0) Selected Add Selected To Cart Compare Selected Email Selected Clear Selected Top Of Search

---

Filtered By:

Products: Proteins

Clear Filters

If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.