DCP2

decapping mRNA 2

Decapping metalloenzyme that catalyzes the cleavage of the cap structure on mRNAs. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. Necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Plays a role in replication-dependent histone mRNA degradation. Has higher activity towards mRNAs that lack a poly(A) tail. Has no activity towards a cap structure lacking an RNA moiety.

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Proteins (3)

Type

Recombinant (3)

Target

DCP2 (3)

Publications

No (3)

Tag

GST (1)

His (2)

Species

Human (3)

Source

E. coli (1)

Wheat Germ Extract (1)

Yeast (1)

Purification

Purified (1)

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Human DCP2 Protein (Recombinant His) (aa1-385) - LS-G21789

Source:

E. coli

Tag:

His

Molecular Weight:

48.5 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human DCP2 Protein (Recombinant His) (aa1-385) - LS-G23432

Source:

Yeast

Tag:

His

Molecular Weight:

46.4 kD

Price:

100 µg/$446; 20 µg/$336; 1 mg/$1,460

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Human DCP2 Protein (Recombinant GST) (Full Length) - LS-G36889

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

68.09 kDa

Price:

10 µg/$479; 25 µg/$670

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