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DCN / Decorin

decorin

DCN / Decorin is a small cellular or pericellular matrix proteoglycan that is closely related in structure to biglycan protein. The encoded protein and biglycan are thought to be the result of a gene duplication. This protein is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly. It contains one attached glycosaminoglycan chain. This protein is capable of suppressing the growth of various tumor cell lines. There are multiple alternatively spliced transcript variants known for this gene. This gene is a candidate gene for Marfan syndrome.

Gene Name: decorin
Synonyms: DCN, CSCD, Decorin proteoglycan, PG-S2, PG40, Proteoglycan core protein, SLRR1B, Small leucine-rich protein 1B, PGII, PGS2, Bone proteoglycan II, Decorin, DSPG2
Target Sequences: NM_001920 NP_001911.1 P07585

Publications (3)

1
Inhibition of Pediatric Glioblastoma Tumor Growth by the Anti-Cancer Agent OKN-007 in Orthotopic Mouse Xenografts. Coutinho de Souza P, Mallory S, Smith N, Saunders D, Li XN, McNall-Knapp RY, Fung KM, Towner RA. PloS one. 2015 10:e0134276. (WB, Flo; Human, Rat) [Full Text Article] [PubMed:26248280] [PMC:PMC4527837]
2
Databases for technical aspects of immunohistochemistry. Furukawa S, Nagaike M, Ozaki K. Journal of toxicologic pathology. 2017 30:79-107. (IHC; Canine) [Full Text Article] [PubMed:28190929] [PMC:PMC5293696] Related Antibodies: LS-B33.
3
Lung Ablation with Irreversible Electroporation Promotes Immune Cell Infiltration by Sparing Extracellular Matrix Proteins and Vasculature: Implications for Immunotherapy. Masashi Fujimori, Yasushi Kimura, Eisuke Ueshima, Damian E Dupuy, Prasad S Adusumilli, Stephen B Solomon, Govindarajan Srimathveeravalli. Bioelectricity. 2021 September;3:204-214. [Full Text Article] [PubMed:34734168] [PMC:PMC8558078]

☰ Filters
Products
Proteins (26)
Over-Expression Lysate (6)
Recombinant (20)
DCN / Decorin (26)
No (26)
6His, C-terminus (2)
6His, N-terminus (2)
Fc, N-terminus (1)
GST (1)
His (6)
His, C-Terminal (2)
His,C-terminus (2)
His-SUMO (1)
Myc-DDK (Flag) (9)
Cow (1)
Dog (1)
Human (16)
Mouse (5)
293T Cells (3)
Baculovirus (1)
E. coli (7)
HEK 293 Cells (7)
Human (1)
Human Cells (2)
Mammalian Cells (2)
Wheat Germ Extract (1)
Yeast (2)
Purified (5)
Low endotoxin level (9)
DCN / Decorin Protein - Recombinant Decorin By SDS-PAGE
Select
E. coli
His
37.8 kDa
10 µg/$259; 50 µg/$331; 100 µg/$482; 200 µg/$602; 1 mg/$1,553; 500 µg/$1,156; 5 mg/$2,481; 2 mg/$1,723
Select
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
39kD
10 µg/$233; 50 µg/$277; 500 µg/$725; 1 mg/$1,113
DCN / Decorin Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
E. coli
6His, N-terminus
39.9 kDa
1 mg/$1,679; 100 µg/$500; 20 µg/$364
DCN / Decorin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
39.75 kDa
100 µg/$494
DCN / Decorin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
39.75 kDa
100 µg/$494
Select
E. coli
His-SUMO
51.9 kD
1 mg/$1,679; 100 µg/$500; 20 µg/$364
Select
Yeast
His
37.9 kD
1 mg/$1,683; 100 µg/$499; 20 µg/$364
DCN / Decorin Protein - 12.5% SDS-PAGE of human DCN stained with Coomassie Blue
Select
Wheat Germ Extract
GST
65.23 kDa
10 µg/$479; 25 µg/$670
Select
293T Cells
Myc-DDK (Flag)
39.75 kDa
20 µg/$150
Select
293T Cells
Myc-DDK (Flag)
39.75 kDa
20 µg/$150
DCN / Decorin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
37.9 kDa
20 µg/$150
DCN / Decorin Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
Yeast
6His, N-terminus
100 µg/$679; 20 µg/$429; 1 mg/$1,973
DCN / Decorin Protein - Purified recombinant protein DCN was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
37.9 kDa
20 µg/$1,107
DCN / Decorin Protein - Purified recombinant protein DCN was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
37.9 kDa
20 µg/$1,107
DCN / Decorin Protein - Purified recombinant protein DCN was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
17.4 kDa
20 µg/$1,107
DCN / Decorin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
37.9 kDa
100 µg/$494
DCN / Decorin Protein
Select
E. coli
His
50 µg/$361; 250 µg/$739; 10 µg/$261
Select
E. coli
119 AA
His
Less than 0.1 EU/µg protein (determined by LAL method).
13.2 kDa
10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531
Select
Baculovirus
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
38.8 kDa
10 µg/$248; 50 µg/$317
Select
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
39.0 kDa
10 µg/$233; 50 µg/$277
Select
Mammalian Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
38.8 kDa
10 µg/$248; 50 µg/$299
Select
HEK 293 Cells
Fc, N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
63. kDa
100 µg/$483
Select
Human
His, C-Terminal
Less than 1.0 EU/µg protein (determined by LAL method).
38.8kD
10 µg/$248; 50 µg/$299; 500 µg/$725; 1 mg/$1,067
Select
E. coli
His, C-Terminal
Less than 1.0 EU/µg protein (determined by LAL method).
38.8kD
10 µg/$248; 50 µg/$321; 500 µg/$725; 1 mg/$1,021
Select
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
39.4 kDa
100 µg/$450
Viewing 1-25 of 26 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).