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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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DCN / Decorin

decorin

DCN / Decorin is a small cellular or pericellular matrix proteoglycan that is closely related in structure to biglycan protein. The encoded protein and biglycan are thought to be the result of a gene duplication. This protein is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly. It contains one attached glycosaminoglycan chain. This protein is capable of suppressing the growth of various tumor cell lines. There are multiple alternatively spliced transcript variants known for this gene. This gene is a candidate gene for Marfan syndrome.

Gene Name: decorin
Synonyms: DCN, CSCD, Decorin proteoglycan, PG-S2, PG40, Proteoglycan core protein, SLRR1B, Small leucine-rich protein 1B, PGII, PGS2, Bone proteoglycan II, Decorin, DSPG2
Target Sequences: NM_001920 NP_001911.1 P07585

Publications (2)

1
Inhibition of Pediatric Glioblastoma Tumor Growth by the Anti-Cancer Agent OKN-007 in Orthotopic Mouse Xenografts. Coutinho de Souza P, Mallory S, Smith N, Saunders D, Li XN, McNall-Knapp RY, Fung KM, Towner RA. PloS one. 2015 10:e0134276. (WB, Flo; Human, Rat) [Full Text Article] [PubMed:26248280] [PMC:PMC4527837] Related Antibodies: LS-B8177.
2
Databases for technical aspects of immunohistochemistry. Furukawa S, Nagaike M, Ozaki K. Journal of toxicologic pathology. 2017 30:79-107. (IHC; Canine) [Full Text Article] [PubMed:28190929] [PMC:PMC5293696] Related Antibodies: LS-B33.

Filtered by: None
Type
Over-Expression Lysate (10)
Recombinant (19)
Target
DCN / Decorin (29)
Tag
6His,C-terminus (4)
6His,N-terminus (1)
GST (1)
His (7)
His + SUMO (1)
His, C-Terminal (2)
Myc + DDK (13)
Species
Cow (1)
Human (17)
Mouse (4)
Source
293T Cells (3)
E. coli (7)
HEK 293 Cells (11)
Human (1)
Human Cells (2)
Sf9 Cells (2)
Wheat Germ Extract (1)
Yeast (2)
Purification
Purified (12)
Low Endotoxin Level
Low endotoxin level (5)
Biologically Active
Biologically active (1)
Publications
No (29)
Showing 1-25 of 29 results

Mouse DCN / Decorin Protein (Recombinant 6His,C-terminus) (Gly17-Lys354) - LS-G40228
Human Cells
6His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
39kD
10µg  $185.00; 50µg  $225.00; 500µg  $635.00; 1mg  $995.00

Human DCN / Decorin Protein (Recombinant His) (aa20-359) - LS-G22496
E. coli
His
41.8 kD
1000µg  $1,245.00; 500µg  $785.00; 200µg  $475.00; 50µg  $275.00; 10µg  $235.00; 100µg  $355.00
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image

Mouse DCN / Decorin Protein (Recombinant His) (aa35-354) - LS-G22888
Yeast
His
37.9 kD
1000µg  $1,845.00; 500µg  $1,155.00; 200µg  $680.00; 50µg  $325.00; 10µg  $275.00; 100µg  $435.00

Mouse DCN / Decorin Protein (Recombinant His + SUMO) (aa35-354) - LS-G20662
E. coli
His + SUMO
51.9 kD
1000µg  $1,845.00; 500µg  $1,155.00; 200µg  $695.00; 50µg  $325.00; 10µg  $275.00; 100µg  $445.00

Mouse DCN / Decorin Protein (Recombinant 6His,C-terminus) - LS-G135591
Sf9 Cells
6His,C-terminus
38.8kDa
2µg  $195.00; 10µg  $255.00; 1mg  $5,460.00

Human DCN / Decorin Protein (Recombinant His) - LS-G19276
E. coli
His
37.6 kDa
2µg  $195.00; 10µg  $255.00; 1mg  $5,460.00

Human DCN / Decorin Protein (Recombinant His) - LS-G3272
E. coli
His
50µg 0.25mg/ml  $315.00; 250µg 0.25mg/ml  $695.00
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image

Human DCN / Decorin Protein (Recombinant His) (aa31-359) - LS-G14788
E. coli
His
37.8 kDa
10µg  $245.00; 50µg  $375.00; 100µg  $445.00; 200µg  $635.00; 1mg  $1,620.00; 500µg  $725.00
Recombinant Decorin By SDS-PAGE

Human DCN / Decorin Protein (Recombinant His) (aa45-152) - LS-G14789
E. coli
His
13.7 kDa
10µg  $245.00; 50µg  $375.00; 100µg  $445.00; 200µg  $635.00; 1mg  $1,620.00; 500µg  $725.00

Human DCN / Decorin Protein (Recombinant GST) (Full Length) - LS-G28165
Wheat Germ Extract
GST
65.23 kDa
10µg  $425.00; 25µg  $590.00
12.5% SDS-PAGE of human DCN stained with Coomassie Blue

Human DCN / Decorin Protein (Recombinant 6His,C-terminus) (aa17-359) - LS-G5226
HEK 293 Cells
6His,C-terminus
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
38.8 kDa-45 kDa
20µg  $365.00; 100µg  $920.00
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image

Human DCN / Decorin Protein (Recombinant His, C-Terminal) (Gly17-Lys359) - LS-G55702
Human
His, C-Terminal
Less than 1.0 EU/µg protein (determined by LAL method).
38.8kD
10µg  $195.00; 50µg  $245.00; 500µg  $635.00; 1mg  $950.00

Human DCN / Decorin Protein (Recombinant His, C-Terminal) (Gly17-Lys359) - LS-G55705
E. coli
His, C-Terminal
Less than 1.0 EU/µg protein (determined by LAL method).
38.8kD
10µg  $195.00; 50µg  $265.00; 500µg  $635.00; 1mg  $890.00

Cow DCN / Decorin Protein (Recombinant 6His,N-terminus) (aa31-360) - LS-G57158
Yeast
6His,N-terminus
1mg  $2,205.00; 500µg  $1,395.00; 200µg  $980.00; 100µg  $605.00; 50µg  $395.00; 10µg  $325.00
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Human DCN / Decorin Protein (Recombinant Myc + DDK) (Full Length) - LS-G65093
HEK 293 Cells
Myc + DDK
17.4 kDa
20µg  $890.00
Purified recombinant protein DCN was analyzed by SDS-PAGE gel and Coomassie Blue Staining

Human DCN / Decorin Protein (Recombinant Myc + DDK) (Full Length) - LS-G65091
HEK 293 Cells
Myc + DDK
37.9 kDa
20µg  $890.00
Purified recombinant protein DCN was analyzed by SDS-PAGE gel and Coomassie Blue Staining

Human DCN / Decorin Protein (Recombinant Myc + DDK) (Full Length) - LS-G65092
HEK 293 Cells
Myc + DDK
37.9 kDa
20µg  $890.00
Purified recombinant protein DCN was analyzed by SDS-PAGE gel and Coomassie Blue Staining

Human DCN / Decorin Protein (Over-Expression Lysate Myc + DDK) (Full Length) - LS-G74818
293T Cells
Myc + DDK
39.75 kDa
20µg  $195.00

Human DCN / Decorin Protein (Over-Expression Lysate Myc + DDK) (Full Length) - LS-G74819
293T Cells
Myc + DDK
39.75 kDa
20µg  $195.00

Human DCN / Decorin Protein (Over-Expression Lysate Myc + DDK) (Full Length) - LS-G74820
293T Cells
Myc + DDK
37.9 kDa
20µg  $195.00
Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate

Human DCN / Decorin Protein (Recombinant 6His,C-terminus) (aa31-359) - LS-G134548
Sf9 Cells
6His,C-terminus
37.1kDa
2µg  $195.00; 10µg  $255.00; 1mg  $5,460.00

DCN / Decorin Protein (Over-Expression Lysate Myc + DDK) (Full Length) - LS-G118308
HEK 293 Cells
Myc + DDK
39.75 kDa
100µg  $365.00
Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate

DCN / Decorin Protein (Over-Expression Lysate Myc + DDK) (Full Length) - LS-G126889
HEK 293 Cells
Myc + DDK
39.75 kDa
100µg  $365.00
Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate

Human DCN / Decorin Protein (Recombinant His) (Met1-Lys359) - LS-G97380
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
39.4 kDa
100µg  $415.00; 200µg  $680.00

DCN / Decorin Protein (Over-Expression Lysate Myc + DDK) (Full Length) - LS-G107472
HEK 293 Cells
Myc + DDK
21.5 kDa
100µg  $345.00
Showing 1-25 of 29 results

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If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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