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DBI / ACBD1

diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)

EP / DBI is diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene.

Gene Name: diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
Synonyms: DBI, ACBP, Acyl-CoA-binding protein, CCK-RP, ACBD1, GABA receptor modulator, EP, Endozepine
Target Sequences: NM_020548 NP_065438.1 P07108

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Products
Proteins (10)
Over-Expression Lysate (2)
Recombinant (8)
DBI / ACBD1 (10)
No (10)
10His, N-terminus + Myc, C-terminus (1)
6His, N-terminus (1)
GST (1)
GST, N-terminus (1)
His (2)
His-S (1)
Myc-DDK (Flag) (3)
Human (7)
Mouse (1)
Rat (1)
293T Cells (1)
E. coli (5)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (2)
DBI / ACBD1 Protein - Recombinant Diazepam Binding Inhibitor By SDS-PAGE
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E. coli
His-S
15.8 kDa
10 µg/$249; 50 µg/$307; 100 µg/$385; 200 µg/$482; 1 mg/$1,325; 500 µg/$962; 5 mg/$2,204; 2 mg/$1,480
DBI / ACBD1 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
10His, N-terminus + Myc, C-terminus
16.9 kDa
1 mg/$1,679; 100 µg/$598; 20 µg/$405
DBI / ACBD1 Protein
Select
E. coli
6His, N-terminus
15.9 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
DBI / ACBD1 Protein - Recombinant Diazepam Binding Inhibitor By SDS-PAGE
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E. coli
His
11.4 kDa
10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
DBI / ACBD1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
11.6 kDa
100 µg/$494
DBI / ACBD1 Protein - Purified recombinant protein DBI was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
11.6 kDa
20 µg/$1,107
DBI / ACBD1 Protein - 12.5% SDS-PAGE of human DBI stained with Coomassie Blue
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Wheat Germ Extract
GST
38.2 kDa
10 µg/$479; 25 µg/$670
DBI / ACBD1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
11.6 kDa
20 µg/$150
DBI / ACBD1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
2 µg/$439
DBI / ACBD1 Protein
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E. coli
His
100 µg/$342; 500 µg/$641; 20 µg/$254
Viewing 1-10 of 10 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).