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DBF4B / DRF1

DBF4 homolog B (S. cerevisiae)

Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S and M phases. The complex CDC7-DBF4B selectively phosphorylates MCM2 subunit at 'Ser-40' and then is involved in regulating the initiation of DNA replication during cell cycle.

Gene Name:	DBF4 homolog B (S. cerevisiae)
Synonyms:	DBF4B, ASKL1, Dbf4-related factor 1, DRF1, Chiffon homolog B, DBF4 homolog B (S. cerevisiae), Protein DBF4 homolog B, ASK-like protein 1, CHIFB, ZDBF1B
Target Sequences:	NM_025104 NP_079380.2 Q8NFT6

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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