DAZ4

deleted in azoospermia 4

DAZ4 is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications; one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat; the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified; this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains two copies of the 10.8 kb repeat. Alternatively spliced transcript variants encoding different isoforms have been described.

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Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

DAZ4 (5)

Publications

No (5)

Tag

GST (1)

His, N-Terminal (1)

Myc-DDK (Flag) (3)

Species

Human (4)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (1)

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DAZ4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G111153

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

43.9 kDa

Price:

100 µg/$494

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Human DAZ4 Protein (Recombinant His, N-Terminal) - LS-G145099

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

43.9 kDa

Price:

50 µg/$419

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Human DAZ4 Protein (Recombinant GST) (Full Length) - LS-G34666

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

70.5 kDa

Price:

10 µg/$479; 25 µg/$670

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Human DAZ4 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G72585

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

43.9 kDa

Price:

20 µg/$1,107

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Human DAZ4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G92933

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

43.9 kDa

Price:

20 µg/$150

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