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DAPK2 / DAP Kinase 2
death-associated protein kinase 2
Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Regulates both type I apoptotic and type II autophagic cell deaths signal, depending on the cellular setting. The former is caspase-dependent, while the latter is caspase-independent and is characterized by the accumulation of autophagic vesicles. Acts as a mediator of anoikis and a suppressor of beta-catenin-dependent anchorage-independent growth of malignant epithelial cells. May play a role in granulocytic maturation.Isoform 2 is not regulated by calmodulin. It can phosphorylate MYL9. It can induce membrane blebbing and autophagic cell death.
| Gene Name: | death-associated protein kinase 2 |
| Family/Subfamily: | Protein Kinase , DAPK |
| Synonyms: | DAPK2, DAP-kinase-related protein 1, DRP-1, DRP1, DAP kinase 2 |
| Target Sequences: | NM_014326 NP_055141.2 Q9UIK4 |
Publications (1)
1
Lyn kinase promotes erythroblast expansion and late-stage development. Karur VG, Lowell CA, Besmer P, Agosti V, Wojchowski DM. Blood. 2006 108:1524-32.
[PubMed:16705093]
[PMC:PMC1895506]
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DAPK2 / DAP Kinase 2
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(46)
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(51)
DAPK2 / DAP Kinase 2 Goat anti-Human Polyclonal (aa359-370) Antibody
Rabbit, Mouse, Rat, Hamster, Horse, Bat, Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
DAPK2 / DAP Kinase 2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
DAPK2 / DAP Kinase 2 Mouse anti-Human Monoclonal (OTI1C5) Antibody
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
DAPK2 / DAP Kinase 2 Mouse anti-Human Monoclonal (Carrier-free) (OTI1C5) Antibody
Dog, Rat, Human, Monkey
Flo, IF, IHC, IP, WB
Unconjugated, Carrier-free
100 µg/$511
DAPK2 / DAP Kinase 2 Mouse anti-Human Monoclonal (OTI1F7) Antibody
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
DAPK2 / DAP Kinase 2 Mouse anti-Human Monoclonal (Carrier-free) (OTI1F7) Antibody
Human
IF, IHC, IP, WB
Unconjugated, Carrier-free
100 µg/$511
DAPK2 / DAP Kinase 2 Mouse anti-Human Monoclonal (OTI1C8) Antibody
Flo, IHC, IHC-P, WB
Unconjugated
100 µl/$434
DAPK2 / DAP Kinase 2 Mouse anti-Human Monoclonal (Carrier-free) (OTI1C8) Antibody
Human
Flo, IHC, IP, WB
Unconjugated, Carrier-free
100 µg/$511
DAPK2 / DAP Kinase 2 Mouse anti-Human Monoclonal (Carrier-free) (1B5) Antibody
Human
IF, IHC, IP, WB
Unconjugated, Carrier-free
100 µg/$511
DAPK2 / DAP Kinase 2 Rabbit anti-Human Polyclonal (aa284-333) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µl/$460
DAPK2 / DAP Kinase 2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
DAPK2 / DAP Kinase 2 Mouse anti-Human Monoclonal (OTI1B10) Antibody
Flo, IF, WB
Unconjugated
100 µl/$434
DAPK2 / DAP Kinase 2 Mouse anti-Human Monoclonal (Carrier-free) (OTI1B10) Antibody
Human
Flo, IF, IP, WB
Unconjugated, Carrier-free
100 µg/$511
DAPK2 / DAP Kinase 2 Rabbit anti-Human Polyclonal (pSer318) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
DAPK2 / DAP Kinase 2 Rabbit anti-Human Polyclonal (aa222-370) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
DAPK2 / DAP Kinase 2 Rabbit anti-Human Polyclonal (260-340 aa) Antibody
Mouse, Rat, Human
ELISA, IF, IHC
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
DAPK2 / DAP Kinase 2 Rabbit anti-Human Polyclonal (pSer318) Antibody
Mouse, Human
ELISA, IF, IHC
Unconjugated
100 µg/$357
DAPK2 / DAP Kinase 2 Rabbit anti-Human Polyclonal (aa40-70) Antibody
Flo, IHC, WB
Unconjugated
200 µl/$734
DAPK2 / DAP Kinase 2 Rabbit anti-Human Polyclonal (aa40-70) (Biotin) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
Biotin Conjugated
200 µl/$952
DAPK2 / DAP Kinase 2 Rabbit anti-Human Polyclonal (aa40-70) (FITC) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
FITC Conjugated
200 µl/$952
DAPK2 / DAP Kinase 2 Rabbit anti-Human Polyclonal (aa40-70) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
DAPK2 / DAP Kinase 2 Rabbit anti-Human Polyclonal (aa40-70) (APC) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
APC Conjugated
200 µl/$952
DAPK2 / DAP Kinase 2 Rabbit anti-Human Polyclonal (aa40-70) (PE) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
PE Conjugated
200 µl/$952
DAPK2 / DAP Kinase 2 Rabbit anti-Human Polyclonal (aa40-70) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
DAPK2 / DAP Kinase 2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$341
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