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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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DAPK2 / DAP Kinase 2

death-associated protein kinase 2

Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Regulates both type I apoptotic and type II autophagic cell deaths signal, depending on the cellular setting. The former is caspase-dependent, while the latter is caspase-independent and is characterized by the accumulation of autophagic vesicles. Acts as a mediator of anoikis and a suppressor of beta-catenin-dependent anchorage-independent growth of malignant epithelial cells. May play a role in granulocytic maturation.Isoform 2 is not regulated by calmodulin. It can phosphorylate MYL9. It can induce membrane blebbing and autophagic cell death.

Gene Name: death-associated protein kinase 2
Family/Subfamily: Protein Kinase , DAPK
Synonyms: DAPK2, DAP-kinase-related protein 1, DRP-1, DRP1, DAP kinase 2
Target Sequences: NM_014326 NP_055141.2 Q9UIK4

Publications (1)

1
Lyn kinase promotes erythroblast expansion and late-stage development. Karur VG, Lowell CA, Besmer P, Agosti V, Wojchowski DM. Blood. 2006 108:1524-32. [PubMed:16705093] [PMC:PMC1895506]

Filtered by: None
Target
DAPK2 / DAP Kinase 2 (50)
Reactivity
Human (45)
Mouse (26)
Rat (10)
Bat (1)
Dog (1)
Hamster (1)
Horse (1)
Monkey (2)
Rabbit (1)
Application
IHC (29)
IHC-P (14)
WB (41)
Flo (13)
ELISA (29)
IF (12)
IP (6)
Peptide-ELISA (3)
Host
rabbit (32)
mouse (17)
goat (1)
Isotype
IgG (27)
IgG1 (2)
IgG1,k (7)
IgG2b (4)
IgG3 (4)
Clonality
monoclonal mc (17)
polyclonal pc (33)
Clone
1B5 (2)
OTI1B10 (2)
OTI1C5 (2)
OTI1C8 (2)
OTI1F7 (2)
Format
AP Conjugated (4)
APC Conjugated (3)
Azide-free (2)
Biotin Conjugated (4)
Carrier-free (5)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (3)
Unconjugated (28)
Epitope
aa38-65 (8)
aa40-70 (8)
aa222-370 (4)
260-340 aa (2)
Arg314 (1)
aa281-370 (1)
aa284-333 (1)
aa289-308 (1)
aa325-342 (1)
aa359-370 (1)
pSer318 (1)
Publications
No (50)
Showing 1-25 of 50 results

IHC-plus™ DAPK2 / DAP Kinase 2 Antibody (clone 1B5) LS-B9958
Mouse Monoclonal [clone 1B5] (IgG2b) to Human DAPK2 / DAP Kinase 2
Human
IF, IHC, IHC-P, IP, WB
Unconjugated
50µl 1mg/ml  $425.00
Anti-DAPK2 / DRP1 antibody IHC staining of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-DAPK2 mouse monoclonal antibody  immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY DAPK2.

IHC-plus™ DAPK2 / DAP Kinase 2 Antibody (aa359-370) LS-B3593
Goat Polyclonal to Human DAPK2 / DAP Kinase 2
Rabbit, Mouse, Rat, Hamster, Horse, Bat, Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µg 0.5mg/ml  $425.00
Anti-DAPK2 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.
Anti-DAPK2 antibody IHC of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.

IHC-plus™ DAPK2 / DAP Kinase 2 Antibody LS-B556
Rabbit Polyclonal (IgG) to Human DAPK2 / DAP Kinase 2
Mouse, Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50µg 1mg/ml  $545.00
Anti-DAPK2 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-DAPK2 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

DAPK2 / DAP Kinase 2 Antibody (clone OTI1C5) LS-C115139
Mouse Monoclonal [clone OTI1C5] (IgG3) to Human DAPK2 / DAP Kinase 2
Flo, IF, IHC, IHC-P, WB
Unconjugated
100µl 0.76mg/ml  $345.00
Immunohistochemical staining of paraffin-embedded colon tissue using anti-DAPK2 mouse monoclonal antibody. (Dilution 1:50).
Immunohistochemical staining of paraffin-embedded Kidney tissue using anti-DAPK2 mouse monoclonal antibody. (Dilution 1:50).

DAPK2 / DAP Kinase 2 Antibody (clone OTI1C5, Carrier-free) LS-C799357
Mouse Monoclonal [clone OTI1C5] (IgG3) to Human DAPK2 / DAP Kinase 2
Dog, Rat, Human, Monkey
Flo, IF, IHC, IP, WB
Unconjugated, Carrier-free
100µg  $395.00
Immunohistochemical staining of paraffin-embedded colon tissue using anti-DAPK2 mouse monoclonal antibody. (Dilution 1:50).
Immunohistochemical staining of paraffin-embedded Kidney tissue using anti-DAPK2 mouse monoclonal antibody. (Dilution 1:50).

DAPK2 / DAP Kinase 2 Antibody (clone OTI1F7) LS-C115127
Mouse Monoclonal [clone OTI1F7] (IgG1) to Human DAPK2 / DAP Kinase 2
IF, IHC, IHC-P, WB
Unconjugated
100µl 0.78mg/ml  $345.00
Immunohistochemical staining of paraffin-embedded Kidney tissue using anti-DAPK2 mouse monoclonal antibody. (Dilution 1:50).
Immunohistochemical staining of paraffin-embedded lung tissue using anti-DAPK2 mouse monoclonal antibody. (Dilution 1:50).

DAPK2 / DAP Kinase 2 Antibody (clone OTI1F7, Carrier-free) LS-C797244
Mouse Monoclonal [clone OTI1F7] (IgG1) to Human DAPK2 / DAP Kinase 2
Human
IF, IHC, IP, WB
Unconjugated, Carrier-free
100µg  $395.00
Immunohistochemical staining of paraffin-embedded Kidney tissue using anti-DAPK2 mouse monoclonal antibody. (Dilution 1:50).
Immunohistochemical staining of paraffin-embedded lung tissue using anti-DAPK2 mouse monoclonal antibody. (Dilution 1:50).

DAPK2 / DAP Kinase 2 Antibody (clone OTI1C8) LS-C115128
Mouse Monoclonal [clone OTI1C8] (IgG3) to Human DAPK2 / DAP Kinase 2
Flo, IHC, IHC-P, WB
Unconjugated
100µl 0.72mg/ml  $345.00
Immunohistochemical staining of paraffin-embedded lung tissue using anti-DAPK2 mouse monoclonal antibody. (Dilution 1:50).
Immunohistochemical staining of paraffin-embedded pancreas tissue using anti-DAPK2 mouse monoclonal antibody. (Dilution 1:50).

DAPK2 / DAP Kinase 2 Antibody (clone OTI1C8, Carrier-free) LS-C797245
Mouse Monoclonal [clone OTI1C8] (IgG3) to Human DAPK2 / DAP Kinase 2
Human
Flo, IHC, IP, WB
Unconjugated, Carrier-free
100µg  $395.00
Immunohistochemical staining of paraffin-embedded lung tissue using anti-DAPK2 mouse monoclonal antibody. (Dilution 1:50).
Immunohistochemical staining of paraffin-embedded pancreas tissue using anti-DAPK2 mouse monoclonal antibody. (Dilution 1:50).

DAPK2 / DAP Kinase 2 Antibody (clone 1B5, Carrier-free) LS-C797243
Mouse Monoclonal [clone 1B5] (IgG2b) to Human DAPK2 / DAP Kinase 2
Human
IF, IHC, IP, WB
Unconjugated, Carrier-free
100µg  $395.00
Anti-DAPK2 / DRP1 antibody IHC staining of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-DAPK2 mouse monoclonal antibody  immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY DAPK2.

DAPK2 / DAP Kinase 2 Antibody (clone OTI1B10) LS-C115233
Mouse Monoclonal [clone OTI1B10] (IgG2b) to Human DAPK2 / DAP Kinase 2
Flo, IF, WB
Unconjugated
100µl 0.84mg/ml  $345.00
Anti-DAPK2 mouse monoclonal antibody  immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY DAPK2.
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY DAPK2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-DAPK2.

DAPK2 / DAP Kinase 2 Antibody (clone OTI1B10, Carrier-free) LS-C797282
Mouse Monoclonal [clone OTI1B10] (IgG2b) to Human DAPK2 / DAP Kinase 2
Human
Flo, IF, IP, WB
Unconjugated, Carrier-free
100µg  $395.00
Anti-DAPK2 mouse monoclonal antibody  immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY DAPK2.
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY DAPK2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-DAPK2.

IHC-plus™ DAPK2 / DAP Kinase 2 Antibody (aa284-333) LS-B7647
Rabbit Polyclonal (IgG) to Human DAPK2 / DAP Kinase 2
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA
Unconjugated
50µl 1mg/ml  $425.00
Anti-DAPK2 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.

DAPK2 / DAP Kinase 2 Antibody LS-C807034
Rabbit Polyclonal (IgG) to Human DAPK2 / DAP Kinase 2
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00
Immunofluorescence Image
Western blot Image

DAPK2 / DAP Kinase 2 Antibody (aa40-70) LS-C64505
Rabbit Polyclonal (IgG) to Human DAPK2 / DAP Kinase 2
Flo, IHC, WB
Unconjugated
200µl  $590.00

DAPK2 / DAP Kinase 2 Antibody (aa40-70, Biotin) LS-C218909
Rabbit Polyclonal (IgG) to Human DAPK2 / DAP Kinase 2
Mouse, Human
ELISA, Flo, IHC, WB
Biotin Conjugated
200µl  $740.00

DAPK2 / DAP Kinase 2 Antibody (aa40-70, FITC) LS-C218910
Rabbit Polyclonal (IgG) to Human DAPK2 / DAP Kinase 2
Mouse, Human
ELISA, Flo, IHC, WB
FITC Conjugated
200µl  $740.00

DAPK2 / DAP Kinase 2 Antibody (aa40-70, AP) LS-C218907
Rabbit Polyclonal (IgG) to Human DAPK2 / DAP Kinase 2
Mouse, Human
ELISA, Flo, IHC, WB
AP Conjugated
200µl  $740.00

DAPK2 / DAP Kinase 2 Antibody (aa40-70, APC) LS-C218908
Rabbit Polyclonal (IgG) to Human DAPK2 / DAP Kinase 2
Mouse, Human
ELISA, Flo, IHC, WB
APC Conjugated
200µl  $740.00

DAPK2 / DAP Kinase 2 Antibody (aa40-70, Azide-free, HRP) LS-C218911
Rabbit Polyclonal (IgG) to Human DAPK2 / DAP Kinase 2
Mouse, Human
ELISA, Flo, IHC, WB
HRP Conjugated, Azide-free
200µl  $740.00

DAPK2 / DAP Kinase 2 Antibody (aa40-70, PE) LS-C218912
Rabbit Polyclonal (IgG) to Human DAPK2 / DAP Kinase 2
Mouse, Human
ELISA, Flo, IHC, WB
PE Conjugated
200µl  $740.00

DAPK2 / DAP Kinase 2 Antibody (phospho-Ser318) LS-C198870
Rabbit Polyclonal (IgG) to Human DAPK2 / DAP Kinase 2
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA
Unconjugated
50µl 1mg/ml  $265.00; 100µl 1mg/ml  $325.00
Immunohistochemistry analysis of paraffin-embedded human skeletal muscle, using DAPK2 (Phospho-Ser318) Antibody. The picture on the right is blocked with the phospho peptide.
Immunofluorescence analysis of COS7 cells, using DAPK2 (Phospho-Ser318) Antibody. The picture on the right is blocked with the phospho peptide.

DAPK2 / DAP Kinase 2 Antibody (aa222-370) LS-C369509
Rabbit Polyclonal (IgG) to Human DAPK2 / DAP Kinase 2
Human
ELISA, IHC, IHC-P
Unconjugated
50µg  $285.00; 100µg  $385.00
Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using antibody at 1:100 dilution.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Immunohistochemistry of paraffin-embedded human breast cancer tissue using antibody at 1:100 dilution.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

DAPK2 / DAP Kinase 2 Antibody (260-340 aa) LS-C381725
Rabbit Polyclonal (IgG) to Human DAPK2 / DAP Kinase 2
Mouse, Rat, Human
ELISA, IF, IHC
Unconjugated
50µl 1mg/ml  $235.00; 100µl 1mg/ml  $265.00; 200µl 1mg/ml  $335.00

DAPK2 / DAP Kinase 2 Antibody (aa40-70) LS-C100744
Rabbit Polyclonal to Human DAPK2 / DAP Kinase 2
Mouse, Human
IHC, IHC-P, WB
Unconjugated
400µl  $325.00
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Formalin-fixed and paraffin-embedded human skeletal muscle tissue reacted with DAPK2 Antibody (N-term V55) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Showing 1-25 of 50 results

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).