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DAO / D Amino Acid Oxidase

D-amino-acid oxidase

Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids.

Gene Name: D-amino-acid oxidase
Synonyms: DAO, D-amino acid oxidase, DAAO, D Amino Acid Oxidase, DAMOX, OXDA
Target Sequences: NM_001917 NP_001908.3 P14920

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).