DACH2

dachshund family transcription factor 2

Transcription factor that is involved in regulation of organogenesis. Seems to be a regulator for SIX1 and SIX6. Seems to act as a corepressor of SIX6 in regulating proliferation by directly repressing cyclin-dependent kinase inhibitors, including the p27Kip1 promoter. Is recruited with SIX6 to the p27Kip1 promoter in embryonal retina. SIX6 corepression seems also to involve NCOR1, TBL1, HDAC1 and HDAC3. May be involved together with PAX3, SIX1, and EYA2 in regulation of myogenesis. In the developing somite, expression of DACH2 and PAX3 is regulated by the overlying ectoderm, and DACH2 and PAX3 positively regulate each other's expression (By similarity). Probably binds to DNA via its DACHbox-N domain.

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Proteins (7)

Type

Over-Expression Lysate (6)

Recombinant (1)

Target

DACH2 (7)

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No (7)

Tag

Myc-DDK (Flag) (7)

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Human (4)

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293T Cells (3)

HEK 293 Cells (4)

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Human DACH2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G92974

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

61.8 kDa

Price:

20 µg/$150

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Human DACH2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G92975

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

47 kDa

Price:

20 µg/$150

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Human DACH2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G92976

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

65.1 kDa

Price:

20 µg/$215

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DACH2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G108002

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

65.1 kDa

Price:

100 µg/$710

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DACH2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G125813

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

61.8 kDa

Price:

100 µg/$494

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DACH2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G125814

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

47 kDa

Price:

100 µg/$494

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Human DACH2 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G72598

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

47 kDa

Price:

20 µg/$1,107

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