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D-Binding Protein / DBP

D site of albumin promoter (albumin D-box) binding protein

This transcriptional activator recognizes and binds to the sequence 5'-RTTAYGTAAY-3' found in the promoter of genes such as albumin, CYP2A4 and CYP2A5. It is not essential for circadian rhythm generation, but modulates important clock output genes. May be a direct target for regulation by the circadian pacemaker component clock. May affect circadian period and sleep regulation.

Gene Name: D site of albumin promoter (albumin D-box) binding protein
Synonyms: DBP, D-binding protein, DABP, Albumin D box-binding protein, TaxREB302, D site-binding protein
Target Sequences: NM_001352 NP_001343.2 Q10586

Publications (1)

1
Hippocampal clock regulates memory retrieval via Dopamine and PKA-induced GluA1 phosphorylation. Shunsuke Hasegawa, Hotaka Fukushima, Hiroshi Hosoda, Tatsurou Serita, Rie Ishikawa, Tomohiro Rokukawa, Ryouka Kawahara-Miki, Yue Zhang, Miho Ohta, Shintaro Okada, Toshiyuki Tanimizu, Sheena A Josselyn, Paul W Frankland, Satoshi Kida. Nature communications. 2019 Dec;10:5766. [Full Text Article] [PubMed:31852900] [PMC:PMC6920429] Related Antibodies: LS-B3479.

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Proteins (3)
Over-Expression Lysate (2)
Recombinant (1)
D-Binding Protein / DBP (3)
No (3)
GST, N-terminus (1)
Myc-DDK (Flag) (2)
Human (2)
293T Cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
D-Binding Protein / DBP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
34.2 kDa
100 µg/$494
D-Binding Protein / DBP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
34.2 kDa
20 µg/$150
D-Binding Protein / DBP Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).