CYR61

cysteine-rich, angiogenic inducer, 61

Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up-regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5. CYR61-mediated gene regulation is dependent on heparin-binding. Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1. Promotes cell adhesion and adhesive signaling through integrin alpha-6/beta-1, cell migration through integrin alpha-v/beta-5 and cell proliferation through integrin alpha-v/beta-3.

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Products

Proteins (14)

Type

Over-Expression Lysate (2)

Recombinant (12)

Target

CYR61 (14)

Publications

No (14)

Tag

10His, N-terminus (1)

6His, N-terminus (1)

6His-SUMO, N-terminus (1)

Fc, C-terminus (2)

GST (2)

GST, N-terminus (1)

His-T7 (2)

Myc-DDK (Flag) (2)

Species

Human (10)

Mouse (3)

Source

293T Cells (1)

E. coli (6)

HEK 293 Cells (1)

Human Cells (1)

Mammalian Cells (1)

Wheat Germ Extract (3)

Yeast (1)

Purification

Purified (6)

Low Endotoxin Level

Low endotoxin level (3)

Biologically Active

Biologically active (2)

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Human CYR61 Protein (Recombinant) - LS-G93

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.1 ng/µg of protein (less than 1EU/µg).

Molecular Weight:

39.5 kDa

Price:

5 µg/$268; 20 µg/$349

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Mouse CYR61 Protein (Recombinant 6His, N-terminus) (aa25-379) - LS-G22885

Source:

Yeast

Tag:

6His, N-terminus

Molecular Weight:

41.14 kD

Price:

100 µg/$499; 20 µg/$364; 1 mg/$1,683

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Human CYR61 Protein (Recombinant) (aa25-381) - LS-G5810

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Molecular Weight:

39.4 kDa

Price:

5 µg/$282; 100 µg/$1,186; 500 µg/$2,269

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Mouse CYR61 Protein (Recombinant 10His, N-terminus) (Full Length) - LS-G136992

Source:

E. coli

Tag:

10His, N-terminus

Molecular Weight:

42.6 kDa

Price:

1 mg/$1,679; 100 µg/$500; 20 µg/$364

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Human CYR61 Protein (Recombinant 6His-SUMO, N-terminus) (aa25-381) - LS-G56201

Source:

E. coli

Tag:

6His-SUMO, N-terminus

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human CYR61 Protein (Recombinant Fc, C-terminus) (Thr25-Asp381) - LS-G39376

Source:

Human Cells

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

66.5kD

Price:

10 µg/$281; 50 µg/$395; 500 µg/$1,585; 1 mg/$2,157

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CYR61 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G118514

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

41.8 kDa

Price:

100 µg/$494

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Human CYR61 Protein (Recombinant GST) (Full Length) - LS-G29008

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

64.9 kDa

Price:

2 µg/$439

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Human CYR61 Protein (Recombinant GST) (Full Length) - LS-G29009

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

67.65 kDa

Price:

2 µg/$439

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Human CYR61 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75367

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

41.8 kDa

Price:

20 µg/$150

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Human CYR61 Protein (Recombinant GST, N-terminus) (aa293-381) - LS-G58963

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human CYR61 Protein (Recombinant Fc, C-terminus) (Thr25-Asp381) - LS-G139067

Source:

Mammalian Cells

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

66.5 kDa

Price:

10 µg/$281; 50 µg/$389

Select

Human CYR61 Protein (Recombinant His-T7) (aa178-381) - LS-G15738

Source:

E. coli

Tag:

His-T7

Molecular Weight:

26.9 kDa

Price:

10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284

Select

Mouse CYR61 Protein (Recombinant His-T7) (aa176-379) - LS-G15737

Source:

E. coli

Tag:

His-T7

Molecular Weight:

26.8 kDa

Price:

10 µg/$268; 50 µg/$362; 100 µg/$577; 200 µg/$722; 1 mg/$1,755; 500 µg/$1,325; 5 mg/$2,708; 2 mg/$1,934

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