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CYP4B1

cytochrome P450, family 4, subfamily B, polypeptide 1

CYP4B1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. In rodents, the homologous protein has been shown to metabolize certain carcinogens; however, the specific function of the human protein has not been determined. Two transcript variants encoding slightly different isoforms have been found for this gene.

Gene Name: cytochrome P450, family 4, subfamily B, polypeptide 1
Family/Subfamily: Cytochrome P450 , not assigned-Cytochrome P450
Synonyms: CYP4B1, Cytochrome P450 4B1, CYPIVB1, Cytochrome p450 IVb1, Cytochrome P450-HP, P-450HP
Target Sequences: NM_000779 NP_000770.2 P13584

Publications (1)

1
Downregulation of the cytochrome P450 4B1 protein confers a poor prognostic factor in patients with urothelial carcinomas of upper urinary tracts and urinary bladder. Jen-Tai Lin, Ti-Chun Chan, Chien-Feng Li, Steven K H Huan, Yu-Feng Tian, Peir-In Liang, Cheng-Tang Pan, Yow-Ling Shiue. APMIS: acta pathologica, microbiologica, et immunologica Scandinavica. 2019 April;127:170-180. [Full Text Article] [PubMed:30803053] Related Antibodies: LS-C167236.

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Proteins (4)
Over-Expression Lysate (2)
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CYP4B1 (4)
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GST (1)
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Human (3)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
CYP4B1 Protein - Purified recombinant protein CYP4B1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
58.9 kDa
20 µg/$1,107
CYP4B1 Protein - 12.5% SDS-PAGE of human CYP4B1 stained with Coomassie Blue
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Wheat Germ Extract
GST
82.06 kDa
2 µg/$439
CYP4B1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
58.8 kDa
100 µg/$494
CYP4B1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
58.8 kDa
20 µg/$150
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).