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CYP4B1

cytochrome P450, family 4, subfamily B, polypeptide 1

CYP4B1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. In rodents, the homologous protein has been shown to metabolize certain carcinogens; however, the specific function of the human protein has not been determined. Two transcript variants encoding slightly different isoforms have been found for this gene.

Gene Name: cytochrome P450, family 4, subfamily B, polypeptide 1
Family/Subfamily: Cytochrome P450 , not assigned-Cytochrome P450
Synonyms: CYP4B1, Cytochrome P450 4B1, CYPIVB1, Cytochrome p450 IVb1, Cytochrome P450-HP, P-450HP
Target Sequences: NM_000779 NP_000770.2 P13584

Publications (1)

1
Downregulation of the cytochrome P450 4B1 protein confers a poor prognostic factor in patients with urothelial carcinomas of upper urinary tracts and urinary bladder. Jen-Tai Lin, Ti-Chun Chan, Chien-Feng Li, Steven K H Huan, Yu-Feng Tian, Peir-In Liang, Cheng-Tang Pan, Yow-Ling Shiue. APMIS: acta pathologica, microbiologica, et immunologica Scandinavica. 2019 April;127:170-180. [Full Text Article] [PubMed:30803053] Related Antibodies: LS-C167236.

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Antibodies (20)
Proteins (4)
ELISA Kits (1)
Cell-Based (1)
Over-Expression Lysate (2)
Primary (20)
Recombinant (2)
CYP4B1 (25)
Human (21)
Mouse (10)
Rat (3)
Bat (3)
Bovine (3)
Dog (3)
Guinea pig (3)
Hamster (3)
Horse (3)
Rabbit (3)
IHC (8)
IHC-P (3)
WB (19)
ELISA (4)
IF (2)
IP (1)
Peptide-ELISA (2)
rabbit (19)
mouse (1)
IgG (19)
polyclonal pc (20)
96-Well Microplate (1)
APC Conjugated (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (12)
aa72-121 (4)
110-190 aa, Internal (1)
aa141-190 (1)
aa331-362 (1)
No (24)
Yes (1)
Adherent Cell Cultures (1)
GST (1)
Myc-DDK (Flag) (3)
Human (3)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
CYP4B1 Antibody - Formalin-fixed and paraffin-embedded human lung carcinoma reacted with CYP4B1 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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CYP4B1 Rabbit anti-Human Polyclonal (aa331-362) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
CYP4B1 Antibody - CYP4B1 antibody Western blot of Fetal Brain lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CYP4B1 Rabbit anti-Human Polyclonal (aa72-121) Antibody
Human
WB
Unconjugated
100 µl/$424
CYP4B1 Antibody - CYP4B1 antibody Western blot of Fetal Brain lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CYP4B1 Rabbit anti-Human Polyclonal (aa72-121) (HRP) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Horse, Bat, Human
WB
HRP Conjugated
100 µl/$469
CYP4B1 Antibody - CYP4B1 antibody Western blot of Fetal Brain lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CYP4B1 Rabbit anti-Human Polyclonal (aa72-121) (Biotin) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Horse, Bat, Human
WB
Biotin Conjugated
100 µl/$469
CYP4B1 Antibody - CYP4B1 antibody Western blot of Fetal Brain lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CYP4B1 Rabbit anti-Human Polyclonal (aa72-121) (FITC) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Horse, Bat, Human
WB
FITC Conjugated
100 µl/$469
CYP4B1 Antibody - 1:100 staining mouse liver tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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CYP4B1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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CYP4B1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
100 µg/$331
CYP4B1 Antibody - Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using Cytochrome P450 4B1 Antibody. The picture on the right is blocked with the synthesized peptide.
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CYP4B1 Rabbit anti-Human Polyclonal (aa141-190) Antibody
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
CYP4B1 Antibody - Western blot of CYP4B1 antibody
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CYP4B1 Rabbit anti-Human Polyclonal (110-190 aa, Internal) Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CYP4B1 Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using Cytochrome P450 4B1 antibody.
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CYP4B1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
CYP4B1 Antibody - Immunohistochemistry of paraffin-embedded human brain tissue at dilution 1:100
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CYP4B1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
CYP4B1 Antibody - Western blot analysis of extracts of MCF7 cell lines.
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CYP4B1 Rabbit anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
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CYP4B1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
100 µg/$749
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CYP4B1 Rabbit anti-Human Polyclonal (HRP) Antibody
Mouse, Human
WB
HRP Conjugated
100 µl/$937
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CYP4B1 Rabbit anti-Human Polyclonal (Biotin) Antibody
Mouse, Human
WB
Biotin Conjugated
100 µl/$937
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CYP4B1 Rabbit anti-Human Polyclonal (FITC) Antibody
Mouse, Human
WB
FITC Conjugated
100 µl/$937
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CYP4B1 Rabbit anti-Human Polyclonal (APC) Antibody
Mouse, Human
WB
APC Conjugated
100 µl/$937
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CYP4B1 Rabbit anti-Human Polyclonal (PE) Antibody
Mouse, Human
WB
PE Conjugated
100 µl/$937
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CYP4B1 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
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CYP4B1 Mouse anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µg/$705
CYP4B1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
58.8 kDa
100 µg/$494
CYP4B1 ELISA Kit
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Cell-Based
96-Well Microplate
Human
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$618
CYP4B1 Protein - 12.5% SDS-PAGE of human CYP4B1 stained with Coomassie Blue
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Wheat Germ Extract
GST
82.06 kDa
2 µg/$439
CYP4B1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
58.8 kDa
20 µg/$150
CYP4B1 Protein - Purified recombinant protein CYP4B1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
58.9 kDa
20 µg/$1,107
Viewing 1-25 of 25 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).