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2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
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Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
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Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565
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CYP2C18 / CYP2C
cytochrome P450, family 2, subfamily C, polypeptide 18
CYP2C18 / CYP2C is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum but its specific substrate has not yet been determined. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. An additional gene, CYP2C17, was once thought to exist; however, CYP2C17 is now considered an artefact based on a chimera of CYP2C18 and CYP2C19. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
| Gene Name: | cytochrome P450, family 2, subfamily C, polypeptide 18 |
| Family/Subfamily: | Cytochrome P450 , not assigned-Cytochrome P450 |
| Synonyms: | CYP2C18, CYP2C17, CYPIIC18, Cytochrome P450 2C18, Cytochrome P450-6b/29c, p450IIC17, p450-6B/29C, CPCI, CYP2C, Unspecific monooxygenase |
| Target Sequences: | NM_000772 NP_000763.1 P33260 |
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