CYP2B6

cytochrome P450, family 2, subfamily B, polypeptide 6

This gene, CYP2B6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize some xenobiotics, such as the anti-cancer drugs cyclophosphamide and ifosphamide. Transcript variants for this gene have been described; however, it has not been resolved whether these transcripts are in fact produced by this gene or by a closely related pseudogene, CYP2B7. Both the gene and the pseudogene are located in the middle of a CYP2A pseudogene found in a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q.

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Proteins (4)

Type

Over-Expression Lysate (2)

Recombinant (2)

Target

CYP2B6 (4)

Publications

No (4)

Tag

GST (1)

Myc-DDK (Flag) (3)

Species

Human (3)

Source

293T Cells (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human CYP2B6 Protein (Recombinant GST) (Full Length) - LS-G28130

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

82.7 kDa

Price:

10 µg/$479; 25 µg/$670

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Human CYP2B6 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75408

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

56.1 kDa

Price:

20 µg/$150

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Human CYP2B6 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65354

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

56.1 kDa

Price:

20 µg/$1,107

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CYP2B6 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99144

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

56.1 kDa

Price:

100 µg/$494

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